Astaxanthin attenuates contrast-induced acute kidney injury in rats by inhibiting dynaminrelated protein 1-mediated mitochondrial fission through activating SIRT1 pathway

被引：0
|
作者：
张成 [1 ]
机构：
[1] Dept Cardiol,Affil Hosp,Xuzhou Med Univ
来源：
China Medical Abstracts (Internal Medicine) | 2022年 / 39卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R692 [肾疾病];
学科分类号：
1002 ; 100210 ;
摘要：
Objective To investigate whether astaxanthin(AST) down-regulates dynamin-related protein 1(Drpl) through activating the silent mating type information regulation 2 homolog-1(SIRT1) signaling pathway,thereby attenuating contrast-induced acute kidney injury.Methods Forty adult male SpragueDawley rats weighing 160-180 g were randomly divided into five groups:sham surgery group(Sham group),
引用
收藏
页码：227 / 228
页数：2
相关论文
共 50 条
  • [1] Protective effect of astaxanthin against contrast-induced acute kidney injury via SIRT1-p53 pathway in rats
    Gao, Dongmei
    Wang, Hu
    Xu, Yang
    Zheng, Di
    Zhang, Quan
    Li, Wenhua
    [J]. INTERNATIONAL UROLOGY AND NEPHROLOGY, 2019, 51 (02) : 351 - 358
  • [2] Protective effect of astaxanthin against contrast-induced acute kidney injury via SIRT1-p53 pathway in rats
    Dongmei Gao
    Hu Wang
    Yang Xu
    Di Zheng
    Quan Zhang
    Wenhua Li
    [J]. International Urology and Nephrology, 2019, 51 : 351 - 358
  • [3] Effect of Curcumin Intervention on Contrast-induced Kidney Injury in Experimental Rats through Upregulating the Expression of Sirt1
    Li Wenhua
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2016, 68 (16) : C179 - C179
  • [4] Effect of astaxanthin intervention on contrast induced acute kidney injury through the SIRT1/FOXO3a signal
    Li Wenhua
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2016, 68 (16) : C179 - C179
  • [5] Astaxanthin attenuates contrast-induced acute kidney injury in rats via ROS/NLRP3 inflammasome
    Song, Liang
    Yao, Shun
    Zheng, Di
    Xuan, Yongli
    Li, Wenhua
    [J]. INTERNATIONAL UROLOGY AND NEPHROLOGY, 2022, 54 (06) : 1355 - 1364
  • [6] Astaxanthin attenuates contrast-induced acute kidney injury in rats via ROS/NLRP3 inflammasome
    Liang Song
    Shun Yao
    Di Zheng
    Yongli Xuan
    Wenhua Li
    [J]. International Urology and Nephrology, 2022, 54 : 1355 - 1364
  • [7] Astaxanthin attenuates contrast agent-induced acute kidney injury in vitro and in vivo via the regulation of SIRT1/FOXO3a expression
    Nana Liu
    Jing Chen
    Dongmei Gao
    Wenhua Li
    Di Zheng
    [J]. International Urology and Nephrology, 2018, 50 : 1171 - 1180
  • [8] Astaxanthin attenuates contrast agent-induced acute kidney injury in vitro and in vivo via the regulation of SIRT1/FOXO3a expression
    Liu, Nana
    Chen, Jing
    Gao, Dongmei
    Li, Wenhua
    Zheng, Di
    [J]. INTERNATIONAL UROLOGY AND NEPHROLOGY, 2018, 50 (06) : 1171 - 1180
  • [9] Melatonin Attenuates Diabetic Myocardial Microvascular Injury through Activating the AMPK/SIRT1 Signaling Pathway
    Wang, Bin
    Li, Jinyu
    Bao, Mi
    Chen, Runji
    Li, Haiyan
    Lu, Binger
    Chen, Meixin
    Huang, Danmei
    Zhang, Yanmei
    Gao, Fenfei
    Shi, Ganggang
    [J]. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2021, 2021
  • [10] Rapamycin attenuates mitochondrial injury and renal tubular cell apoptosis in experimental contrast-induced acute kidney injury in rats
    Yang, Xueyan
    Yan, Xiaojie
    Yang, Dingping
    Zhou, Junke
    Song, Jie
    Yang, Dingwei
    [J]. BIOSCIENCE REPORTS, 2018, 38
12345