Engineering isogenic neuronal models of ATXN3 knockout in Machado-Joseph Disease patient cells by CRISPR/Cas9

被引：0
|
作者：
Fernandes, A. R. [1 ,2 ,3 ]
Adao, D. [1 ,3 ]
Lopes, S. M. [1 ,2 ,3 ]
Henriques, D. [1 ,2 ,3 ]
Pena, F. [1 ,2 ,3 ]
Dias, M. [1 ,3 ]
Santana, M. M. [1 ,2 ,3 ]
Perdigao, P. [1 ,2 ,3 ]
Almeida, L. P. [1 ,3 ,4 ]
机构：
[1] Univ Coimbra, Ctr Neurosci & Cell Biol, Coimbra, Portugal
[2] Univ Coimbra, Inst Interdisciplinary Res, Coimbra, Portugal
[3] Univ Coimbra, Ctr Innovat Biomed & Biotechnol, Coimbra, Portugal
[4] Univ Coimbra, Fac Pharm, Coimbra, Portugal
来源：
HUMAN GENE THERAPY | 2024年 / 35卷 / 3-4期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
P297
引用
收藏
页码：A142 / A143
页数：2
相关论文
共 45 条
  • [41] FROM GENETIC ASSOCIATION TO DISEASE BIOLOGY: 2D AND 3D HUMAN IPSC MODELS OF NEUROPSYCHIATRIC DISORDERS AND CRISPR/CAS9 GENOME EDITING
    Duan, Jubao
    Penzes, Peter
    Gejman, Pablo
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2019, 29 : S763 - S764
  • [42] Effect of lncRNA XLOC_005950 knockout by CRISPR/Cas9 gene editing on energy metabolism and proliferation in osteosarcoma MG63 cells mediated by hsa-miR-542-3p
    Jia, Zhen
    Wang, Yadong
    Sun, Xiaoya
    Zhao, Xuefeng
    Zhang, Yan
    Xu, Shuangyan
    Wang, Yisheng
    Li, Yuebai
    ONCOLOGY LETTERS, 2021, 22 (03)
  • [43] BIALLELIC LOSS OF ATM AND BIRC3 IN CELLS WITH (11Q) INCREASES GENOMIC INSTABILITY AND ACCELERATES THE EXPANSION OF TUMOR CLONE IN CRISPR/CAS9 MODELS AND PATIENTS WITH CHRONIC LYMPHATIC LEUKEMIA
    Quijada Alamo, M.
    Hernandez Sanchez, M.
    Ordonez, J. L.
    Rodriguez Vicente, A. E.
    Alonso Perez, V
    Garcia-Tunon, I
    Martin Martin, A.
    Perez Carretero, C.
    Del Pozo, M.
    Pujante, S.
    Ramos, M. A.
    Herrero, A. B.
    Parker, H.
    Garcia, J. L.
    Benito, R.
    Strefford, J. C.
    Hernandez Rivas, J. M.
    HAEMATOLOGICA, 2018, 103 : 59 - 59
  • [44] A targeted TIM3 Knockout by using CRISPR/Cas9 has no direct Effect on the Function of CD19-specific CAR T Cells in vitro, but could still increase CAR T Cell Persistence
    Schairer, R.
    Moraes, Ribeiro E.
    Korkmaz, F.
    Lengerke, C.
    Schneidawind, D.
    ONCOLOGY RESEARCH AND TREATMENT, 2022, 45 (SUPPL 2) : 123 - 123
  • [45] Generation of gene corrected human isogenic iPSC lines (IDVi003-A_CR13, IDVi003-A_CR21, IDVi003-A_CR24) from an inherited retinal dystrophy patient-derived IPSC line ITM2B-5286-3 (IDVi003-A) carrying the ITM2B c.782A > C variant using CRISPR/Cas9
    Yacoub, Tasnim Ben
    Letellier, Camille
    Wohlschelegel, Juliette
    Condroyer, Christel
    Goureau, Olivier
    Zeitz, Christina
    Audo, Isabelle
    STEM CELL RESEARCH, 2023, 71
12345