Partitioned polygenic scores and extremes of polygenic risk provide mechanistic insights into type 2 diabetes and gestational diabetes in British Pakistani and Bangladeshi populations

被引：0
|
作者：
Hodgson, S. [1 ]
Williamson, A. [1 ]
Stow, D. [1 ]
Jacobs, B. M. [1 ]
Samuel, M. [1 ]
Gafton, J. [1 ]
Zollner, J. [2 ]
Spreckler, M. [1 ]
Langenberg, C. [1 ]
van Heel, D. A. [1 ]
Mathur, R. [1 ]
Siddiqui, M. K. [1 ]
Finer, S. [1 ]
机构：
[1] Queen Mary Univ London, London, England
[2] UCL, London, England
来源：
DIABETOLOGIA | 2024年 / 67卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
179
引用
收藏
页码：S96 / S97
页数：2
相关论文
共 50 条
  • [1] Analyses of type 2 diabetes partitioned polygenic scores among Asian Indian and European populations
    Melhem, A. L.
    Anjana, R. M.
    Bigossi, M.
    Srinivasan, S.
    Venkatesan, R.
    Mohan, V.
    Palmer, C. N. A.
    Siddiqui, M.
    DIABETOLOGIA, 2023, 66 (SUPPL 1) : S128 - S128
  • [2] Polygenic Risk Scores in Type 2 Diabetes and Depression
    Kan, Carol
    Euesden, Jack
    Mccarthy, Mark I.
    Breen, Gerome
    Ismail, Khalida
    Lewis, Cathryn M.
    DIABETES, 2015, 64 : A462 - A462
  • [3] Metabolomic Profiling of Type 2 Diabetes Pathway-Partitioned Polygenic Risk Scores Offers Insights into Disease Etiology
    Sevilla, Magdalena
    Lamiquiz-Moneo, Itziar
    Smith, Kirk
    Canyelles, Marina
    Florez, Jose C.
    Manning, Alisa
    Civeira, Fernando
    Merino, Jordi
    Udler, Miriam
    DIABETES, 2023, 72
  • [4] Gestational Diabetes Mellitus Shares Genetic Risk Factors With Type 1 and Type 2 Diabetes and Is Predicted by Diabetes Polygenic Scores
    Winters, Jessica L. G.
    Jasper, Elizabeth A.
    Hellwege, Jacklyn N.
    Edwards, Todd L.
    Edwards, Digna R. Velez
    GENETIC EPIDEMIOLOGY, 2024, 48 (07) : 391 - 391
  • [5] Polygenic scores, diet quality, and type 2 diabetes risk
    Merino, J.
    Guasch-Ferre, M.
    Li, J.
    Chung, W.
    Ma, B.
    Liang, L.
    Hu, F. B.
    Florez, J. C.
    DIABETOLOGIA, 2020, 63 (SUPPL 1) : S56 - S57
  • [6] Polygenic risk scores for cardiovascular diseases and type 2 diabetes
    Wong, Chi Kuen
    Makalic, Enes
    Dite, Gillian S.
    Whiting, Lawrence
    Murphy, Nicholas M.
    Hopper, John L.
    Allman, Richard
    PLOS ONE, 2022, 17 (12):
  • [7] Integrating polygenic risk scores in the prediction of gestational diabetes risk in China
    Cheng, Jiayi
    Meng, Chan
    Li, Junwei
    Kong, Ziwen
    Zhou, Aifen
    FRONTIERS IN ENDOCRINOLOGY, 2024, 15
  • [8] Systematic Review of Polygenic Risk Scores for Type 1 and Type 2 Diabetes
    Padilla-Martinez, Felipe
    Collin, Francois
    Kwasniewski, Miroslaw
    Kretowski, Adam
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (05)
  • [9] Estimating the prevalence of type 1 and type 2 diabetes in British Bangladeshis and Pakistanis with an ambiguous diabetes phenotype using polygenic risk scores
    Paterson, G. G.
    Liu, T.
    Sankareswaran, A.
    Chandak, G. R.
    Thomas, N. J.
    Weedon, M. N.
    Yajnik, C. S.
    Oram, R.
    Martin, H.
    Finer, S.
    DIABETIC MEDICINE, 2023, 40
  • [10] Using multistate models and polygenic risk scores to understand cardiometabolic disease in British Pakistani and Bangladeshi populations: showcasing the Genes and Health cohort
    Stow, D.
    Tsang, R. S. M.
    Katzourou, I. K.
    Eto, F.
    Samuel, M.
    Holmans, P. A.
    van den Bree, M. B. M.
    Siddiqui, M. K.
    Barroso, I.
    Timpson, N. J.
    Martin, H. C. M.
    Mathur, R.
    Finer, S.
    DIABETOLOGIA, 2024, 67 : S187 - S188
12345