Estimating the prevalence of type 1 and type 2 diabetes in British Bangladeshis and Pakistanis with an ambiguous diabetes phenotype using polygenic risk scores

被引:0
|
作者
Paterson, G. G. [1 ]
Liu, T. [2 ]
Sankareswaran, A. [3 ]
Chandak, G. R. [3 ]
Thomas, N. J. [4 ]
Weedon, M. N. [4 ]
Yajnik, C. S. [5 ]
Oram, R. [4 ]
Martin, H. [2 ]
Finer, S. [6 ]
机构
[1] St Georges Univ Hosp NHS Trust, Nephrol, London, England
[2] Wellcome Sanger Inst, Human Genet Programme, Hinxton, England
[3] CSIR Ctr Cellular & Mol Biol, Hyderabad, India
[4] Univ Exeter, Inst Biomed & Clin Sci, Coll Med & Hlth, Exeter, Devon, England
[5] KEM Hosp & Res Ctr, Diabet Unit, Pune, Maharashtra, India
[6] Queen Mary Univ London, Wolfson Inst Populat Hlth, London, England
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A45 (P44)
引用
收藏
页数:1
相关论文
共 50 条
  • [1] Investigating misclassification of type 1 diabetes in a population-based cohort of British Pakistanis and Bangladeshis using polygenic risk scores
    Liu, Timing
    Sankareswaran, Alagu
    Paterson, Gordon
    Fraser, Diane P.
    Hodgson, Sam
    Huang, Qin Qin
    Heng, Teng Hiang
    Ladwa, Meera
    Thomas, Nick
    van Heel, David A.
    Weedon, Michael N.
    Yajnik, Chittaranjan S.
    Oram, Richard A.
    Chandak, Giriraj R.
    Martin, Hilary C.
    Finer, Sarah
    SCIENTIFIC REPORTS, 2025, 15 (01):
  • [2] Integrating polygenic risk scores in the prediction of type 2 diabetes risk and subtypes in British Pakistanis and Bangladeshis: A population-based cohort study
    Hodgson, Sam
    Huang, Qin Qin
    Sallah, Neneh
    Griffiths, Chris J.
    Newman, William G.
    Trembath, Richard C.
    Wright, John
    Lumbers, R. Thomas
    Kuchenbaecker, Karoline
    van Heel, David
    Mathur, Rohini
    Martin, Hilary C.
    Finer, Sarah
    PLOS MEDICINE, 2022, 19 (05)
  • [3] Systematic Review of Polygenic Risk Scores for Type 1 and Type 2 Diabetes
    Padilla-Martinez, Felipe
    Collin, Francois
    Kwasniewski, Miroslaw
    Kretowski, Adam
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (05)
  • [4] Polygenic Risk Scores in Type 2 Diabetes and Depression
    Kan, Carol
    Euesden, Jack
    Mccarthy, Mark I.
    Breen, Gerome
    Ismail, Khalida
    Lewis, Cathryn M.
    DIABETES, 2015, 64 : A462 - A462
  • [5] Evaluation of polygenic risk scores to differentiate between type 1 and type 2 diabetes
    Shoaib, Muhammad
    Ye, Qiang
    IglayReger, Heidi
    Tan, Meng H.
    Boehnke, Michael
    Burant, Charles F.
    Soleimanpour, Scott A.
    Taliun, Sarah A. Gagliano A.
    GENETIC EPIDEMIOLOGY, 2023, 47 (04) : 303 - 313
  • [6] Gestational Diabetes Mellitus Shares Genetic Risk Factors With Type 1 and Type 2 Diabetes and Is Predicted by Diabetes Polygenic Scores
    Winters, Jessica L. G.
    Jasper, Elizabeth A.
    Hellwege, Jacklyn N.
    Edwards, Todd L.
    Edwards, Digna R. Velez
    GENETIC EPIDEMIOLOGY, 2024, 48 (07) : 391 - 391
  • [7] Polygenic scores, diet quality, and type 2 diabetes risk
    Merino, J.
    Guasch-Ferre, M.
    Li, J.
    Chung, W.
    Ma, B.
    Liang, L.
    Hu, F. B.
    Florez, J. C.
    DIABETOLOGIA, 2020, 63 (SUPPL 1) : S56 - S57
  • [8] Polygenic risk scores for cardiovascular diseases and type 2 diabetes
    Wong, Chi Kuen
    Makalic, Enes
    Dite, Gillian S.
    Whiting, Lawrence
    Murphy, Nicholas M.
    Hopper, John L.
    Allman, Richard
    PLOS ONE, 2022, 17 (12):
  • [9] Partitioned polygenic scores and extremes of polygenic risk provide mechanistic insights into type 2 diabetes and gestational diabetes in British Pakistani and Bangladeshi populations
    Hodgson, S.
    Williamson, A.
    Stow, D.
    Jacobs, B. M.
    Samuel, M.
    Gafton, J.
    Zollner, J.
    Spreckler, M.
    Langenberg, C.
    van Heel, D. A.
    Mathur, R.
    Siddiqui, M. K.
    Finer, S.
    DIABETOLOGIA, 2024, 67 : S96 - S97
  • [10] Combined application of genetic and polygenic risk scores for type 1 diabetes risk prediction
    Qu, Hui-Qi
    Qu, Jingchun
    Bradfield, Jonathan
    Glessner, Joseph
    Chang, Xiao
    March, Michael
    Mentch, Frank D.
    Roizen, Jeffrey D.
    Connolly, John J.
    Sleiman, Patrick
    Hakonarson, Hakon
    DIABETES OBESITY & METABOLISM, 2021, 23 (08): : 2001 - 2003