A computational model of the growth of dendritic spines with synaptic plasticity
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作者:
Elibol, Rahmi
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Middle East Tech Univ, Grad Sch Informat, Ankara, Turkiye
Erzincan Univ, Fac Engn, Erzincan, TurkeyMiddle East Tech Univ, Grad Sch Informat, Ankara, Turkiye
Elibol, Rahmi
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机构:
[1] Middle East Tech Univ, Grad Sch Informat, Ankara, Turkiye
The spines on the dendrites of neurons have many biophysical functions such as increasing the surface area of the dendrites and increasing the input resistance of neuron. It is known that synaptic plasticity is effective in the formation and growth of spines. In this work, a computational model of growth of dendritic spines due to synaptic plasticity is presented. The proposed model is built with spiking neural networks and synaptic dynamics. In the model, the change of synaptic weights is achieved with synaptic plasticity, and the growth of dendritic spines can be demonstrated by using this change.
机构:
Univ Calif Santa Cruz, Dept Mol Cell & Dev Biol, 1156 High St, Santa Cruz, CA 95064 USAUniv Calif Santa Cruz, Dept Mol Cell & Dev Biol, 1156 High St, Santa Cruz, CA 95064 USA
Lu, Ju
Zuo, Yi
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Univ Calif Santa Cruz, Dept Mol Cell & Dev Biol, 1156 High St, Santa Cruz, CA 95064 USAUniv Calif Santa Cruz, Dept Mol Cell & Dev Biol, 1156 High St, Santa Cruz, CA 95064 USA
机构:
Seoul Natl Univ, Sch Biol Sci, Seoul, South KoreaSeoul Natl Univ, Sch Biol Sci, Seoul, South Korea
Choi, Ja Eun
Kaang, Bong-Kiun
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Seoul Natl Univ, Sch Biol Sci, Seoul, South Korea
Seoul Natl Univ, Sch Biol Sci, 1 Gwanangno, Seoul 08826, South KoreaSeoul Natl Univ, Sch Biol Sci, Seoul, South Korea
机构:
Univ Illinois, Neurosci Program, Urbana, IL 61801 USA
Univ Illinois, Coordinated Sci Lab, Urbana, IL 61801 USAUniv Illinois, Neurosci Program, Urbana, IL 61801 USA
Gribkova, Ekaterina D.
Gillette, Rhanor
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Univ Illinois, Neurosci Program, Urbana, IL 61801 USA
Univ Illinois, Dept Mol & Integrat Physiol, Urbana, IL USAUniv Illinois, Neurosci Program, Urbana, IL 61801 USA