A computational model of the growth of dendritic spines with synaptic plasticity

被引:0
|
作者
Elibol, Rahmi [1 ,2 ]
机构
[1] Middle East Tech Univ, Grad Sch Informat, Ankara, Turkiye
[2] Erzincan Univ, Fac Engn, Erzincan, Turkey
关键词
dendritic spines; plasticity; synapse; SPIKING NEURAL-NETWORKS; BASAL GANGLIA; NEURONS;
D O I
10.1109/SIU55565.2022.9864973
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
The spines on the dendrites of neurons have many biophysical functions such as increasing the surface area of the dendrites and increasing the input resistance of neuron. It is known that synaptic plasticity is effective in the formation and growth of spines. In this work, a computational model of growth of dendritic spines due to synaptic plasticity is presented. The proposed model is built with spiking neural networks and synaptic dynamics. In the model, the change of synaptic weights is achieved with synaptic plasticity, and the growth of dendritic spines can be demonstrated by using this change.
引用
收藏
页数:4
相关论文
共 50 条
  • [21] Plasticity and stability of single dendritic spines
    Matsuzaki, Masanori
    Tanaka, Jun-ichi
    Miyazaki, Takashi
    Ellis-Davies, Graham C. R.
    Kasai, Haruo
    NEUROSCIENCE RESEARCH, 2006, 55 : S7 - S7
  • [22] Plasticity of Dendritic Spines: Subcompartmentalization of Signaling
    Colgan, Lesley A.
    Yasuda, Ryohei
    ANNUAL REVIEW OF PHYSIOLOGY, VOL 76, 2014, 76 : 365 - 385
  • [23] Plasticity of calcium channels in dendritic spines
    Yasuda, R
    Sabatini, BL
    Svoboda, K
    NATURE NEUROSCIENCE, 2003, 6 (09) : 948 - 955
  • [24] Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity
    McVicker, Derrick P.
    Awe, Adam M.
    Richters, Karl E.
    Wilson, Rebecca L.
    Cowdrey, Diana A.
    Hu, Xindao
    Chapman, Edwin R.
    Dent, Erik W.
    NATURE COMMUNICATIONS, 2016, 7
  • [25] CALCIUM-REGULATED CONTRACTILE AND CYTOSKELETAL PROTEINS IN DENDRITIC SPINES MAY CONTROL SYNAPTIC PLASTICITY
    FIFKOVA, E
    MORALES, M
    ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1989, 568 : 131 - 137
  • [26] CALCIUM-REGULATED CONTRACTILE AND CYTOSKELETAL PROTEINS IN DENDRITIC SPINES MAY CONTROL SYNAPTIC PLASTICITY
    FIFKOVA, E
    MORALES, M
    CALCIUM, MEMBRANES, AGING, AND ALZHEIMERS DISEASE, 1989, 568 : 131 - 137
  • [27] Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity
    Derrick P. McVicker
    Adam M. Awe
    Karl E. Richters
    Rebecca L. Wilson
    Diana A. Cowdrey
    Xindao Hu
    Edwin R. Chapman
    Erik W. Dent
    Nature Communications, 7
  • [28] Large and Small Dendritic Spines Serve Different Interacting Functions in Hippocampal Synaptic Plasticity and Homeostasis
    Paulin, Joshua J. W.
    Haslehurst, Peter
    Fellows, Alexander D.
    Liu, Wenfei
    Jackson, Joshua D.
    Joel, Zelah
    Cummings, Damian M.
    Edwards, Frances A.
    NEURAL PLASTICITY, 2016, 2016
  • [29] PERFORATED SYNAPSES ON DOUBLE-HEADED DENDRITIC SPINES - A POSSIBLE STRUCTURAL SUBSTRATE OF SYNAPTIC PLASTICITY
    GEINISMAN, Y
    MORRELL, F
    DETOLEDOMORRELL, L
    BRAIN RESEARCH, 1989, 480 (1-2) : 326 - 329
  • [30] Calcium dynamics in spines: link to synaptic plasticity
    Holthoff, K
    Tsay, D
    EXPERIMENTAL PHYSIOLOGY, 2002, 87 (06) : 725 - 731