COBALT (II) NITRATE HEXAHYDRATE AS AN EFFICIENT CATALYST FOR THE SYNTHESIS OF β-AMINO KETONES DERIVATIVES

被引：0

作者：

Deshmukh, Jitendra R. ^{[1
]}

Chaudhar, Uddhav N. ^{[2
]}

Patil, Ajay M. ^{[3
]}

Sonkamble, Shivanand G. ^{[3
]}

机构：

[1] Late Kisandas Gulabchand Kataria Coll, Dept Chem, Daund 413801, MC, India

[2] Kalikadevi Arts Commerce & Sci Coll, Dept Chem, Shirur Kasar 413249, MS, India

[3] Pratisthan Mahavidyalaya, Dept Chem, Paithan Tal Paithan, MS, India

来源：

HETEROCYCLIC LETTERS | 2024年 / 14卷 / 04期

关键词：

Mannich reaction; multi-component reactions; cobalt nitrate; beta-Amino carbonyl compounds; MANNICH-TYPE REACTIONS; AROMATIC-ALDEHYDES; CARBONYL-COMPOUNDS; 3-COMPONENT SYNTHESIS; ONDANSETRON; ANILINES;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Eco- friendly protocol was developed for the synthesis of beta-amino ketones derivatives using the one pot multi-component reaction of aromatic aldehydes, ketones and aromatic amines in presence of cobalt (II) nitrate hexahydrate in ethanol at room temperature via mannich reaction. The advantages of this eco-friendly protocol are numerous, and include the use of an inexpensive catalyst, high to excellent yield, short reaction time and high catalytic activity that can make this method an interesting alternative to multi-step approaches.

引用

页码：777 / 785

页数：9

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