NHC-Catalyzed [3+3] Cycloaddition of 2-(acetoxymethyl)buta-2,3-dienoates with 1 C,3O-bisnucleophiles

被引：0

作者：

Cao, Wei ^{[1
]}

Zhang, Kai ^{[1
]}

Yu, Chenxia ^{[1
]}

Yao, Changsheng ^{[1
]}

机构：

[1] Jiangsu Normal Univ, Sch Chem & Mat Sci, Jiangsu Key Lab Green Synthet Chem Funct Mat, Xuzhou 221116, Jiangsu, Peoples R China

来源：

ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2024年

基金：

中国国家自然科学基金;

关键词：

N-heterocyclic carbene; 2-(acetoxymethyl)buta-2,3-dienoate; 4<italic>H</italic>-pyran; PHOSPHINE CATALYSIS; ACETOXY ALLENOATES; ALLENES; ANNULATIONS; BETA';

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Diverse transformations of allenoates catalyzed by Lewis bases have emerged as a powerful platform for generating new chemical entities in organic synthesis. Herein, an N-heterocyclic carbene (NHC) catalyzed [3+3] cyclization of 2-(acetoxymethyl)buta-2,3-dienoates with 1 C,3O-bisnucleophiles has been developed. This approach provides a facile method to synthesize highly functionalized 4H-pyran derivatives with a broad substrate scope (31 examples, up to 83 % yield).

引用

页数：5

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