NHC-Catalyzed [3+3] Cycloaddition of 2-(acetoxymethyl)buta-2,3-dienoates with 1 C,3O-bisnucleophiles

被引：0
|
作者：
Cao, Wei [1 ]
Zhang, Kai [1 ]
Yu, Chenxia [1 ]
Yao, Changsheng [1 ]
机构：
[1] Jiangsu Normal Univ, Sch Chem & Mat Sci, Jiangsu Key Lab Green Synthet Chem Funct Mat, Xuzhou 221116, Jiangsu, Peoples R China
来源：
ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2024年
基金：
中国国家自然科学基金;
关键词：
N-heterocyclic carbene; 2-(acetoxymethyl)buta-2,3-dienoate; 4<italic>H</italic>-pyran; PHOSPHINE CATALYSIS; ACETOXY ALLENOATES; ALLENES; ANNULATIONS; BETA';
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Diverse transformations of allenoates catalyzed by Lewis bases have emerged as a powerful platform for generating new chemical entities in organic synthesis. Herein, an N-heterocyclic carbene (NHC) catalyzed [3+3] cyclization of 2-(acetoxymethyl)buta-2,3-dienoates with 1 C,3O-bisnucleophiles has been developed. This approach provides a facile method to synthesize highly functionalized 4H-pyran derivatives with a broad substrate scope (31 examples, up to 83 % yield).
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页数：5
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