Patient-reported outcomes from the phase III, randomized, double-blind, placebo-controlled ENGOT-cx11/GOG-3047/ KEYNOTE-A18 Study of pembrolizumab plus concurrent chemoradiotherapy among patients with high-risk, locally advanced cervical cancer

被引:0
|
作者
Randall, Leslie [1 ]
Sukhin, Vladyslav [2 ]
Colombo, Nicoletta [3 ,4 ]
Korach, Jacob [5 ]
Matsumoto, Takashi [6 ]
Lalondrelle, Susan [7 ]
Vizkeleti, Julia [8 ]
Samouelian, Vanessa [9 ]
Salani, Ritu [10 ]
Salman, Pamela [11 ]
Nogueira-Rodrigues, Angelica [12 ]
Ayhan, Ali [13 ]
Frentzas, Sophia [14 ,15 ]
Cueva, Juan [16 ]
Kim, Yong-Man [17 ]
Petru, Edgar [18 ]
Milla, Dency Pilar [19 ]
Sehouli, Jalid [20 ]
Saevets, Valeriya [21 ]
Yamada, Karin [22 ]
Li, Kan [23 ]
Szamreta, Elizabeth [22 ]
Nguyen, Allison Martin [22 ]
Pignata, Sandro [24 ]
Lorusso, Domenica [25 ]
机构
[1] Virginia Commonwealth Univ, Richmond, VA USA
[2] Grigoriev Inst Med Radiol & Oncol, Kharkiv, Ukraine
[3] Univ Milano Bicocca, Milan, Italy
[4] European Inst Oncol IRCCS, Milan, Italy
[5] Sheba Med Ctr, Tel Aviv, Israel
[6] Ehime Univ, Matsuyama, Ehime, Japan
[7] Royal Marsden, London, England
[8] Natl Inst Oncol, Ctr Radiotherapy, Budapest, Hungary
[9] Univ Montreal, Montreal, PQ, Canada
[10] Univ Calif Los Angeles, Los Angeles, CA USA
[11] Oncovida Canc Ctr, Santiago, Chile
[12] Univ Fed Minas Gerais, Belo Horizonte, MG, Brazil
[13] Baskent Univ, Turkish Soc Gynecol Oncol TRSGO, Ankara, Turkiye
[14] Monash Hlth, Melbourne, Vic, Australia
[15] Monash Univ, Melbourne, Vic, Australia
[16] Hosp Clin Univ Santiago Compostela, Dept Med Oncol, Santiago De Compostela, Spain
[17] Univ Ulsan, Asan Med Ctr, Seoul, South Korea
[18] Med Univ Graz, Graz, Austria
[19] Hosp Nacl Guillermo Almenara Irigoyen, Lima, Peru
[20] Charite Univ Med Berlin, Berlin, Germany
[21] Chelyabinsk Reg Clin Ctr Oncol & Nucl Med, Chelyabinsk, Russia
[22] Merck & Co Inc, Rahway, NJ 07065 USA
[23] Merck & Co Inc, N Wales, PA USA
[24] Inst Nazl Tumori IRCCS Fdn G Pascale, Naples, Italy
[25] Univ Cattolica Sacro Cuore, Rome, Italy
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
06
引用
收藏
页码:S9 / S9
页数:1
相关论文
共 50 条
  • [31] Patient-reported outcomes following pembrolizumab or placebo plus pemetrexed and platinum in patients with previously untreated, metastatic, non-squamous non-small-cell lung cancer (KEYNOTE-189): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial
    Garassino, Marina C.
    Gadgeel, Shirish
    Esteban, Emilio
    Felip, Enriqueta
    Speranza, Giovanna
    Domine, Manuel
    Hochmair, Maximilian
    Powell, Steve
    Cheng, Susanna Yee-Shan
    Bischoff, Helge G.
    Peled, Nir
    Reck, Martin
    Hui, Rina
    Garon, Edward B.
    Boyer, Michael
    Wei, Ziwen
    Burke, Thomas
    Pietanza, M. Catherine
    Rodriguez-Abreu, Delvys
    LANCET ONCOLOGY, 2020, 21 (03): : 387 - 397
  • [32] CYCLONE 3: A phase III, randomized, double-blind, placebo-controlled study of abemaciclib in combination with abiraterone plus prednisone in men with high-risk metastatic hormone-sensitive prostate cancer
    Matsubara, N.
    Agarwal, N.
    Smith, M. R.
    Mckay, R. R.
    Todenhofer, T.
    Piulats Rodriguez, J. M.
    Chung, K. L.
    Heirich, D.
    Sherwood, S.
    Schaverien, C.
    Fasnacht, N.
    Lithio, A.
    Nacerddine, K.
    Zhang, T.
    ANNALS OF ONCOLOGY, 2023, 34 : S1582 - S1583
  • [33] Analysis of patient-reported outcomes from the LUME-Lung 1 trial: A randomised, double-blind, placebo-controlled, Phase III study of second-line nintedanib in patients with advanced non-small cell lung cancer
    Novello, Silvia
    Kaiser, Rolf
    Mellemgaard, Anders
    Douillard, Jean-Yves
    Orlov, Sergey
    Krzakowski, Maciej
    von Pawel, Joachim
    Gottfried, Maya
    Bondarenko, Igor
    Liao, Meilin
    Barrueco, Jose
    Gaschler-Markefski, Birgit
    Griebsch, Ingolf
    Palmer, Michael
    Reck, Martin
    EUROPEAN JOURNAL OF CANCER, 2015, 51 (03) : 317 - 326
  • [34] ANALYSIS OF PATIENT-REPORTED OUTCOMES FROM THE LUME-LUNG 1 TRIAL: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE 3 STUDY IN SECOND-LINE ADVANCED NON-SMALL CELL LUNG CANCER (NSCLC) PATIENTS
    Novello, Silvia
    Mellemgaard, Anders
    Kaiser, Rolf
    Douillard, Jean-Yves
    Orlov, Sergei
    Krzakowski, Maciej
    Von Pawel, Joachim
    Gottfried, Maya
    Bondarenko, Igor
    Liao, Meilin
    Barrueco, Jose
    Gaschler-Markefski, Birgit
    Griebsch, Ingolf
    Reck, Martin
    JOURNAL OF THORACIC ONCOLOGY, 2013, 8 : S1207 - S1207
  • [35] Darolutamide plus androgen-deprivation therapy (ADT) in patients with high-risk biochemical recurrence (BCR) of prostate cancer: A phase 3, randomized, double-blind, placebo-controlled study (ARASTEP).
    Chehrazi-Raffle, Alex
    Morgans, Alicia K.
    Gschwend, Jurgen E.
    Shore, Neal D.
    Ross, Ashley
    Feng, Felix Y.
    Hope, Thomas A.
    Trandafir, Lucia
    Kuss, Iris
    Le Berre, Marie-Aude
    Joensuu, Heikki
    Fizazi, Karim
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (4_SUPPL) : TPS254 - TPS254
  • [36] Darolutamide plus androgen-deprivation therapy (ADT) in patients with high-risk biochemical recurrence (BCR) of prostate cancer: A phase 3, randomized, double-blind, placebo-controlled study (ARASTEP).
    Morgans, Alicia K.
    Niazi, Tamim
    Shore, Neal D.
    Gschwend, Juergen E.
    Ross, Ashley
    Hope, Thomas A.
    Chehrazi-Raffle, Alex
    Supiot, Stephane
    Barthelemy, Philippe
    Roder, Andreas
    Gomes, Andrea Juliana
    Imbroda, Bernardo Herrera
    Gratton, Matthieu
    Ruiz, Carmen Belen Congregado
    Joensuu, Heikki
    Dimova-Dobreva, Miryana
    Le Berre, Marie-Aude
    Kuss, Iris
    Fizazi, Karim
    JOURNAL OF CLINICAL ONCOLOGY, 2025, 43 (5_SUPPL) : TPS432 - TPS432
  • [37] Patient-reported outcomes from a randomized, double-blind, placebo controlled, phase III study of baricitinib versus placebo in patients with moderately to severely active rheumatoid arthritis and an inadequate response to methotrexate therapy: results from the RA-BALANCE study
    Yang, Yue
    Xu, Jianhua
    Xu, Jian
    Li, Xingfu
    Hu, Jiankang
    Li, Xiangpei
    Zhang, Xiao
    He, Dongyi
    Bao, Chunde
    Li, Zhijun
    Wang, Guochun
    Zerbini, Cristiano A. F.
    Spindler, Alberto J.
    Kannowski, Carol L.
    Wu, Hanjun
    Ji, Fei
    Zhan, Lujing
    Liu, Mengru
    Li, Zhanguo
    THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2021, 13
  • [38] PROTEUS: A randomized, double-blind, placebo (PBO)-controlled, phase III trial of apalutamide (APA) plus androgen deprivation therapy (ADT) versus PBO plus ADT prior to radical prostatectomy (RP) in patients with localized high-risk or locally advanced prostate cancer (PC)
    Taplin, Mary-Ellen
    Gleave, Martin
    Evans, Christopher P.
    Efstathiou, Eleni
    Kantoff, Philip W.
    Ross, Ashley
    Shore, Neal D.
    Briganti, Alberto
    Hadaschik, Boris A.
    Heidenreich, Axel
    Rooney, Oliver Brendan
    Tian, Shaozhou Ken
    Wetherhold, Lisa
    Xu, Weichun
    Cheng, Shinta
    Brookman-May, Sabine Doris
    Lopez-Gitlitz, Angela
    Kibel, Adam S.
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (06)
  • [39] Double-blind randomized phase II results comparing concurrent high-dose cisplatin chemorradiation (CRT) plus debio 1143 or placebo in high-risk patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN): A GORTEC study
    Bourhis, J.
    Sun, X.
    Pointreau, Y.
    Sire, C.
    Le Tourneau, C.
    Coutte, A.
    Kaminsky-Forrett, M-C.
    Alfonsi, M.
    Boisselier, P.
    Martin, L.
    Delord, J-P.
    Clatot, F.
    Miroir, J.
    Rolland, F.
    Crompton, P.
    Brienza, S.
    Szyldergemajn, S. A.
    Even, C.
    Tao, Y.
    ANNALS OF ONCOLOGY, 2019, 30 : 902 - 902
  • [40] LUX head and neck 2: A randomized, double-blind, placebo-controlled, phase III study of afatinib as adjuvant therapy after chemoradiation in primarily unresected, clinically high-risk, head and neck cancer patients.
    Burtness, Barbara
    Bourhis, Jean
    Vermorken, Jan Baptist
    Dai, Luyan
    Lind, Charlotte
    Ehrnrooth, Eva
    Cohen, Ezra E. W.
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)