Patient-reported outcomes from the phase III, randomized, double-blind, placebo-controlled ENGOT-cx11/GOG-3047/ KEYNOTE-A18 Study of pembrolizumab plus concurrent chemoradiotherapy among patients with high-risk, locally advanced cervical cancer

被引:0
|
作者
Randall, Leslie [1 ]
Sukhin, Vladyslav [2 ]
Colombo, Nicoletta [3 ,4 ]
Korach, Jacob [5 ]
Matsumoto, Takashi [6 ]
Lalondrelle, Susan [7 ]
Vizkeleti, Julia [8 ]
Samouelian, Vanessa [9 ]
Salani, Ritu [10 ]
Salman, Pamela [11 ]
Nogueira-Rodrigues, Angelica [12 ]
Ayhan, Ali [13 ]
Frentzas, Sophia [14 ,15 ]
Cueva, Juan [16 ]
Kim, Yong-Man [17 ]
Petru, Edgar [18 ]
Milla, Dency Pilar [19 ]
Sehouli, Jalid [20 ]
Saevets, Valeriya [21 ]
Yamada, Karin [22 ]
Li, Kan [23 ]
Szamreta, Elizabeth [22 ]
Nguyen, Allison Martin [22 ]
Pignata, Sandro [24 ]
Lorusso, Domenica [25 ]
机构
[1] Virginia Commonwealth Univ, Richmond, VA USA
[2] Grigoriev Inst Med Radiol & Oncol, Kharkiv, Ukraine
[3] Univ Milano Bicocca, Milan, Italy
[4] European Inst Oncol IRCCS, Milan, Italy
[5] Sheba Med Ctr, Tel Aviv, Israel
[6] Ehime Univ, Matsuyama, Ehime, Japan
[7] Royal Marsden, London, England
[8] Natl Inst Oncol, Ctr Radiotherapy, Budapest, Hungary
[9] Univ Montreal, Montreal, PQ, Canada
[10] Univ Calif Los Angeles, Los Angeles, CA USA
[11] Oncovida Canc Ctr, Santiago, Chile
[12] Univ Fed Minas Gerais, Belo Horizonte, MG, Brazil
[13] Baskent Univ, Turkish Soc Gynecol Oncol TRSGO, Ankara, Turkiye
[14] Monash Hlth, Melbourne, Vic, Australia
[15] Monash Univ, Melbourne, Vic, Australia
[16] Hosp Clin Univ Santiago Compostela, Dept Med Oncol, Santiago De Compostela, Spain
[17] Univ Ulsan, Asan Med Ctr, Seoul, South Korea
[18] Med Univ Graz, Graz, Austria
[19] Hosp Nacl Guillermo Almenara Irigoyen, Lima, Peru
[20] Charite Univ Med Berlin, Berlin, Germany
[21] Chelyabinsk Reg Clin Ctr Oncol & Nucl Med, Chelyabinsk, Russia
[22] Merck & Co Inc, Rahway, NJ 07065 USA
[23] Merck & Co Inc, N Wales, PA USA
[24] Inst Nazl Tumori IRCCS Fdn G Pascale, Naples, Italy
[25] Univ Cattolica Sacro Cuore, Rome, Italy
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
06
引用
收藏
页码:S9 / S9
页数:1
相关论文
共 50 条
  • [21] Phase-III-Study for local or locally advanced Prostate Cancer Randomized, double-blind, placebo-controlled Phase-III-Study of Apalutamide in Patients with local High-Risk Prostate Cancer or locally advanced Prostate Cancer receiving primary radiotherapy (ATLAS) - study AP 90/15 of the AUO
    Rexer, H.
    Graefen, M.
    UROLOGE, 2017, 56 (02): : 243 - 244
  • [22] Durvalumab plus gemcitabine and cisplatin in advanced biliary tract cancer (TOPAZ-1): patient-reported outcomes from a randomised, double-blind, placebo-controlled, phase 3 trial
    Burris, Howard A., III
    Okusaka, Takuji
    Vogel, Arndt
    Lee, Myung Ah
    Takahashi, Hidenori
    Breder, Valeriy
    Blanc, Jean-Frederic
    Li, Junhe
    Bachini, Melinda
    Zotkiewicz, Magdalena
    Abraham, Jayne
    Patel, Nikunj
    Wang, Julie
    Ali, Muzammil
    Rokutanda, Nana
    Cohen, Gordon
    Oh, Do-Youn
    LANCET ONCOLOGY, 2024, 25 (05): : 626 - 635
  • [23] Postoperative Adjuvant Lapatinib and Concurrent Chemoradiotherapy Followed by Maintenance Lapatinib Monotherapy in High-Risk Patients With Resected Squamous Cell Carcinoma of the Head and Neck: A Phase III, Randomized, Double-Blind, Placebo-Controlled Study
    Harrington, Kevin
    Temam, Stephane
    Mehanna, Hisham
    D'Cruz, Anil
    Jain, Minish
    D'Onofrio, Ida
    Manikhas, Georgy
    Horvath, Zsuzsanna
    Sun, Yan
    Dietzsch, Stefan
    Dubinsky, Pavol
    Holeckova, Petra
    El-Hariry, Iman
    Franklin, Natalie
    Biswas-Baldwin, Nigel
    Legenne, Philippe
    Wissel, Paul
    Netherway, Thelma
    Farrell, John
    Ellis, Catherine
    Wang-Silvanto, Jing
    Amonkar, Mayur
    Ahmed, Nazma
    Santillana, Sergio
    Bourhis, Jean
    JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (35) : 4202 - +
  • [24] Phase III Study for local or locally advanced Prostate Cancer: Randomized, double-blind, Placebo-controlled Phase 3 Study of Apalutamide in Patients with local High-Risk Prostate Cancer or locally advanced Prostate Cancer receiving primary Radiotherapy (ATLAS) - Study AP 90/15 of the AUO
    Rexer, H.
    Graefen, M.
    Grimm, M. -O.
    AKTUELLE UROLOGIE, 2017, 48 (06) : 520 - +
  • [25] Darolutamide plus androgen-deprivation therapy (ADT) in patients with high-risk biochemical recurrence (BCR) of prostate cancer: A phase III, randomized, double-blind, placebo-controlled study (ARASTEP)
    Morgans, A. K.
    Gschwend, J. E.
    Shore, N. D.
    Ross, A.
    Feng, F.
    Hope, T.
    Trandafir, L.
    Le Berre, M-A.
    Kuss, I.
    Joensuu, H.
    Fizazi, K.
    ANNALS OF ONCOLOGY, 2023, 34 : S997 - S998
  • [26] KEYNOTE-B49: A phase 3, randomized, double-blind, placebo-controlled study of pembrolizumab plus chemotherapy in patients with HR+/HER2-locally recurrent inoperable or metastatic breast cancer
    Rugo, Hope S.
    Sohn, Joohyuk
    Jerez Gilarranz, Yolanda
    Gonzalez-Cortijo, Lucia
    Sonnenblick, Amir
    Sabanathan, Dhanusha
    Pablo Korbenfeld, Ernesto
    Egle, Daniel
    Poirier, Brigitte
    Zagouri, Flora
    Matikas, Alexios
    Aksoy, Sercan
    Demirci, Umut
    Ramos-Elias, Pier
    Im, Seock-Ah
    Cardoso, Fatima
    Jia, Liyi
    Baccan, Carlos
    Tryfonidis, Konstantinos
    Schmid, Peter
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)
  • [27] KEYNOTE-B49: A phase 3, randomized, double-blind, placebo-controlled study of pembrolizumab plus chemotherapy in patients with HR+/HER2-locally recurrent inoperable or metastatic breast cancer
    Schmid, Peter
    Baccan, Carlos
    Guo, Zifang
    Tryfonidis, Kostas
    Rugo, Hope S.
    CANCER RESEARCH, 2022, 82 (04)
  • [28] eVOLVE-Cervical (GOG-3092/ENGOT-cx19/GEICO133-C): A prospective phase III study of volrustomig versus placebo after definitive chemoradiation among women with high-risk, locally advanced cervical cancer
    Randall, Leslie
    Wu, Xiaohua
    Mayadev, Jyoti
    Takekuma, Munetaka
    Estevez-Diz, Maria Del Pilar
    Shapira-Frommer, Ronnie
    Rimel, Bobbie
    Lorusso, Domenica
    Lee, Jung-Yun
    Zhou, Qi
    Zeng, Xiaoling
    Huang, Rochelle
    Krug, Lee
    Oaknin, Ana
    GYNECOLOGIC ONCOLOGY, 2024, 190 : S285 - S285
  • [29] Darolutamide plus androgen-deprivation therapy in patients with high-risk biochemical recurrence of prostate cancer: A phase 3, randomized, double-blind, placebo-controlled study (ARASTEP)
    Chehrazi-Raffle, Alex
    Morgans, Alicia K.
    Gschwed, Jurgen E.
    Shore, Neal D.
    Ross, Ashley
    Feng, Felix Y.
    Hope, Thomas A.
    Nordquist, Luke
    Niazi, Tamim
    Trandafir, Lucia
    Le Berre, Marie-Aude
    Kuss, Iris
    Joensuu, Heikki
    Fizazi, Karim
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
  • [30] Phase 3, randomized, double-blind, placebo-controlled study of pembrolizumab plus chemotherapy in patients with HR+/HER2-locally recurrent inoperable or metastatic breast cancer (mBC): KEYNOTE-B49
    Schmid, Peter
    Sohn, Joo Hyuk
    Jerez Gilarranz, Yolanda
    Gonzalez-Cortijo, Lucia
    Sonnenblick, Amir
    Sabanathan, Dhanusha
    Korbenfeld, Ernesto
    Egle, Daniel
    Poirier, Brigitte
    Zagouri, Flora
    Matikas, Alexios
    Aksoy, Sercan
    Demirci, Umut
    Ramos-Elias, Pier
    Im, Seock-Ah
    Cardoso, Fatima
    Jia, Liyi
    Hirshfield, Kim
    Tryfonidis, Konstantinos
    Rugo, Hope S.
    ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2022, 18 : 233 - 234