The utility of animal models to inform the next generation of human space exploration

被引：0

作者：

Duporge, Isla ^{[1
,2
]}

Pereira, Talmo ^{[3
]}

de Obeso, Santiago Castiello ^{[4
]}

Ross, Julius G. Bright ^{[5
]}

Lee, Stephen J. ^{[2
,6
]}

Hindle, Allyson G. ^{[7
]}

机构：

[1] Princeton Univ, Dept Ecol & Evolutionary Biol, Princeton, NJ 08544 USA

[2] Natl Acad Sci, Washington, DC 20418 USA

[3] Salk Inst Biol Studies, La Jolla, CA USA

[4] Yale Univ, Wu Tsai Inst, New Haven, CT USA

[5] Univ Oxford, Dept Biol, Wildlife Conservat Res Unit, Oxford, England

[6] US Army Res Lab, Army Res Off, Durham, NC USA

[7] Univ Nevada Las Vegas, Sch Life Sci, Las Vegas, NV USA

来源：

NPJ MICROGRAVITY | 2025年 / 11卷 / 01期

关键词：

SOCIAL-ISOLATION; MENTAL-HEALTH; BEHAVIOR; CONSEQUENCES; ENVIRONMENTS; CONFINEMENT; SPACEFLIGHT; PERFORMANCE; TARDIGRADES; PSYCHOLOGY;

D O I：

10.1038/s41526-025-00460-5

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Animals have played a vital role in every stage of space exploration, from early sub-orbital flights to contemporary missions. New physiological and psychological challenges arise with plans to venture deeper into the solar system. Advances in chimeric and knockout animal models, along with genetic modification techniques have enhanced our ability to study the effects of microgravity in greater detail. However, increased investment in the purposeful design of habitats and payloads, as well as in AI-enhanced behavioral monitoring in orbit can better support the ethical and effective use of animals in deep space research.

引用

页数：10

共 50 条

[21] Pioneering Next Steps in Space Exploration
不详
CHEMICAL ENGINEERING PROGRESS, 2018, 114 (06) : 18 - 19
[22] Designing a SoC to Control the Next-Generation Space Exploration Flight Science Instruments
Iturbe, Xabier
Keymeulen, Didier
Ozer, Emre
Yiu, Patrick
Berisford, Daniel
Hand, Kevin
Carlson, Robert
2015 28TH IEEE INTERNATIONAL SYSTEM-ON-CHIP CONFERENCE (SOCC), 2015, : 13 - 18
[23] Next generation rover for lunar exploration
Harrison, Dan A.
Ambrose, Robert
Bluethmann, Bill
Junkin, Lucien
2008 IEEE AEROSPACE CONFERENCE, VOLS 1-9, 2008, : 1 - 14
[24] Utility and limitations of animal models for the functional validation of human sequence variants
Cox, Timothy C.
MOLECULAR GENETICS & GENOMIC MEDICINE, 2015, 3 (05): : 375 - 382
[25] TRANSLATIONAL PSYCHOPHYSIOLOGY: PSYCHOPHYSIOLOGICAL MEASURES IN ANIMAL MODELS CAN INFORM UNDERSTANDING OF HUMAN PSYCHOLOGY
Sable, Jeffrey
Cuthbert, Bruce
PSYCHOPHYSIOLOGY, 2023, 60 : S19 - S19
[26] Human behavior and performance in deep space exploration: next challenges and research gaps
Pagnini, Francesco
Manzey, Dietrich
Rosnet, Elisabeth
Ferravante, Denise
White, Olivier
Smith, Nathan
NPJ MICROGRAVITY, 2023, 9 (01)
[27] Human behavior and performance in deep space exploration: next challenges and research gaps
Francesco Pagnini
Dietrich Manzey
Elisabeth Rosnet
Denise Ferravante
Olivier White
Nathan Smith
npj Microgravity, 9
[28] The next generation space telescope
Albrecht, R
ASTROPHYSICS AND SPACE SCIENCE, 1998, 258 (1-2) : 295 - 299
[29] Creating space for the next generation
Fehmer, Vincent
INTERNATIONAL JOURNAL OF ESTHETIC DENTISTRY, 2022, 17 (04): : 373 - 374
[30] The Next Generation Space Telescope
Beckwith, SVW
QUASARS, AGNS AND RELATED RESEARCH ACROSS 2000, 2001, : 193 - 204

← 1 2 3 4 5 →