Antioxidant Activity of Catecholamines During the Oxidation of Methyl Linoleoate in Triton X-100 Micelles

被引:0
|
作者
Ryabkova, V. A. [1 ]
Tikhonov, I. V. [1 ]
Pliss, E. M. [1 ]
机构
[1] Demidov Yaroslavl State Univ, Yaroslavl 150003, Russia
基金
俄罗斯科学基金会;
关键词
catecholamines; methyl linoleate; antioxidant activity; superoxide anion radicals; superoxide dismutase; CHAIN-BREAKING ANTIOXIDANT; SUBSTITUTED P-HYDROQUINONES; NATURAL POLYPHENOLS; L-DOPA; LINOLEATE; ELECTROCHEMISTRY; ELECTROSPRAY; ADRENALINE;
D O I
10.1134/S1990793124700891
中图分类号
O64 [物理化学(理论化学)、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号
070203 ; 070304 ; 081704 ; 1406 ;
摘要
AbstractThe effect of catecholamines on the oxidation of methyl linoleate in Triton X-100 micelles is studied. It is established that catecholamines do not inhibit oxidation at a physiological pH value of 7.4. Inhibition is only possible in the presence of the superoxide dismutase enzyme or at lower pH levels. The reason for this effect is the interaction of anionic forms of phenols and phenoxyl radicals with oxygen to form superoxide anion radicals. The high values of the inhibition coefficients for catecholamines in the presence of superoxide dismutase are due to the reactions of the resulting orthoquinones, leading to the regeneration of OH groups.
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页码:1279 / 1283
页数:5
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