Antioxidant Activity of Catecholamines During the Oxidation of Methyl Linoleoate in Triton X-100 Micelles

AbstractThe effect of catecholamines on the oxidation of methyl linoleate in Triton X-100 micelles is studied. It is established that catecholamines do not inhibit oxidation at a physiological pH value of 7.4. Inhibition is only possible in the presence of the superoxide dismutase enzyme or at lower pH levels. The reason for this effect is the interaction of anionic forms of phenols and phenoxyl radicals with oxygen to form superoxide anion radicals. The high values of the inhibition coefficients for catecholamines in the presence of superoxide dismutase are due to the reactions of the resulting orthoquinones, leading to the regeneration of OH groups.