Visible-light-induced radical cascade sulfonylation/cyclization towards indole-fused pyridine derivatives

被引：0

作者：

Du, Qin ^{[1
]}

Pan, Ruohan ^{[2
]}

Chen, Yu ^{[2
]}

Tang, Yucai ^{[2
]}

机构：

[1] Cent South Univ, Changde Hosp, Peoples Hosp Changde City 1, Xiangya Sch Med, Changde 415000, Peoples R China

[2] Hunan Univ Arts & Sci, Coll Chem & Mat Engn, Engn Technol Res Ctr Key Preparat Technol Biomed P, Changde 415000, Peoples R China

来源：

RSC ADVANCES | 2025年 / 15卷 / 01期

关键词：

PHOTOREDOX CATALYSIS; ALKYNES SYNTHESIS; DIARYLSULFONES; INHIBITORS; CHLORIDES;

D O I：

10.1039/d4ra08000a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Indole-fused pyridines are an important motif in pharmaceuticals and functional molecules. A visible-light induced Ru(bpy)3Cl2<middle dot>6H2O catalyzed radical cascade sulfonylation/cyclization strategy for the synthesis of indole-fused pyridine derivatives was developed. Diverse indole-fused pyridines bearing different functional groups were obtained in moderate to good yields. Compared with previous work, the easily accessible starting materials, molecular nitrogen as byproduct, and eco-friendly visible light as an energy source all make this transformation more sustainable and practical.

引用

页码：216 / 222

页数：7

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