Unlocking an additive-free and catalyst-free dual approach for reduction of amides to amines

被引:0
|
作者
Chowdhury, Deep [1 ]
Mukherjee, Arup [1 ]
机构
[1] Indian Inst Technol Bhilai, Dept Chem, Durg 491002, Chhattisgarh, India
关键词
HYDROGENATION;
D O I
10.1039/d4cc04606d
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report a two-fold strategy to convert amides to amines in the presence of dimethylamine-borane as the hydrogen source. In the absence of any additive, the formation of the amines resulted from reduction of the amides. On the other hand, in the presence of TMEDA and dimethylamine-borane, tertiary amines were obtained from primary amides in a one-pot fashion.
引用
收藏
页码:1605 / 1608
页数:4
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