Uniquely altered DNA replication fidelity conferred by an amino acid change in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase

被引：0
|
作者：
Lewis, Deborah A. [1 ]
Bebenek, Katarzyna [1 ]
Beard, William A. [1 ]
Wilson, Samuel H. [1 ]
Kunkel, Thomas A. [1 ]
机构：
[1] Laboratory of Structural Biology, NIEHS, National Institutes of Health, Research Triangle Park, NC 27709, United States
来源：
Journal of Biological Chemistry | / 274卷 / 46期
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：32924 / 32930
相关论文
共 50 条
  • [41] Mispair extension fidelity of human immunodeficiency virus type 1 reverse transcriptases with amino acid substitutions affecting Tyr115
    MartinHernandez, AM
    GutierrezRivas, M
    Domingo, E
    MenendezArias, L
    NUCLEIC ACIDS RESEARCH, 1997, 25 (07) : 1383 - 1389
  • [42] LOW FIDELITY OF CELL-FREE DNA-SYNTHESIS BY REVERSE-TRANSCRIPTASE OF HUMAN IMMUNODEFICIENCY VIRUS
    TAKEUCHI, Y
    NAGUMO, T
    HOSHINO, H
    JOURNAL OF VIROLOGY, 1988, 62 (10) : 3900 - 3902
  • [43] Mutations that abrogate human immunodeficiency virus type 1 reverse transcriptase dimerization affect maturation of the reverse transcriptase heterodimer
    Wapling, J
    Moore, KL
    Sonza, S
    Mak, J
    Tachedjian, G
    JOURNAL OF VIROLOGY, 2005, 79 (16) : 10247 - 10257
  • [44] ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase
    Naeger, LK
    Margot, NA
    Miller, MD
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (07) : 2179 - 2184
  • [45] Studies on the effects of truncating α-helix E prime of p66 human immunodeficiency virus type 1 reverse transcriptase on template-primer binding and fidelity of DNA synthesis
    Menendez-Arias, Luis
    Biochemistry, 1998, 37 (47):
  • [46] Incorporation of human immunodeficiency virus type 1 reverse transcriptase into virus-like particles
    Liao, Wei-Hao
    Huang, Kuo-Jung
    Chang, Yu-Fen
    Wang, Shiu-Mei
    Tseng, Ying-Tzu
    Chiang, Chien-Cheng
    Wang, Jaang-Jiun
    Wang, Chin-Tien
    JOURNAL OF VIROLOGY, 2007, 81 (10) : 5155 - 5165
  • [47] FIDELITY OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-I REVERSE-TRANSCRIPTASE IN COPYING NATURAL RNA
    HUBNER, A
    KRUHOFFER, M
    GROSSE, F
    KRAUSS, G
    JOURNAL OF MOLECULAR BIOLOGY, 1992, 223 (03) : 595 - 600
  • [48] Ribonucleoside Triphosphates as Substrate of Human Immunodeficiency Virus Type 1 Reverse Transcriptase in Human Macrophages
    Kennedy, Edward M.
    Gavegnano, Christina
    Nguyen, Laura
    Slater, Rebecca
    Lucas, Amanda
    Fromentin, Emilie
    Schinazi, Raymond F.
    Kim, Baek
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (50) : 39380 - 39391
  • [49] Recombinant human antibodies against the reverse transcriptase of human immunodeficiency virus type-1
    Herschhorn, A
    Admon, A
    Hizi, A
    BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2003, 1648 (1-2): : 154 - 163
  • [50] Modulation of human immunodeficiency virus type 1 synergistic inhibition by reverse transcriptase mutations
    Basavapathruni, Aravind
    Vingerhoets, Johan
    de Bethune, Marie-Pierre
    Chung, Raymond
    Bailey, Christopher M.
    Kim, Jiae
    Anderson, Karen S.
    BIOCHEMISTRY, 2006, 45 (23) : 7334 - 7340
12345