The difference properties of porcine acellular dermal matrix crosslinked by epoxy compound and carbodiimide

被引：0

作者：

Dan, Nian-Hua ^{[1
,3
]}

Dan, Wei-Hua ^{[1
,2
]}

Guan, Lin-Bo ^{[3
]}

Lin, Hai ^{[1
]}

Wang, Kang-Jian ^{[1
]}

机构：

[1] National Engineering Laboratory for Clean Technology of Leather Manufacture, Sichuan University, Chengdu 610065, China

[2] Research Center of Biomedicine Engineering, Chengdu 610065, China

[3] Jiangyin Benshine Bio-technology Co. Ltd., Jiangyin 214432, China

来源：

Gongneng Cailiao/Journal of Functional Materials | 2009年 / 40卷 / 08期

关键词：

Cell culture - Cytotoxicity - Extraction - Glycerol;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Porcine acellular dermal matrix (pADM) was crosslinked by epoxy compound (glycerol polyglycidyl ether)and carbodiimide (EDC) respectively. The properties of pADM, EDC-pADM, EC(GPE)-pADM were mensurated, such as efficiency of crosslinking, XPS, acute toxicity and cytotoxicity. It was showed that glycerol polyglycidyl ether (GPE) was less effective than EDC, hydrophilic performance of EC-pADM was better than EDC-pADM. The acute toxicity of extraction of EC-pADM on mice by mouth did not appeared whereas EC-pADM did. The cytotoxicity of extraction botainted from them respectively weren't observed in L-929 fibroblasts cultivated experiment. It was concluded that the properties of EC-pADM was better than EDC-pADM.

引用

页码：1352 / 1354

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