Engineering the Reaction Pathway of a Non-heme Iron Oxygenase Using Ancestral Sequence Reconstruction

被引:1
|
作者
Yang, Di [1 ,2 ]
Chiang, Chang-Hwa [1 ,2 ]
Wititsuwannakul, Taveechai [1 ]
Brooks, Charles L. [1 ,2 ,4 ]
Zimmerman, Paul M. [1 ]
Narayan, Alison R. H. [1 ,2 ,3 ]
机构
[1] Department of Chemistry, University of Michigan, Ann Arbor,MI,48109, United States
[2] Life Science Institute, University of Michigan, Ann Arbor,MI,48109, United States
[3] Program in Chemical Biology, University of Michigan, Ann Arbor,MI,48109, United States
[4] Enhanced Program in Biophysics, University of Michigan, Ann Arbor,MI,48109, United States
关键词
Hydrogen bonds;
D O I
10.1021/jacs.4c08420
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学科分类号
摘要
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页码:34352 / 34363
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