Engineering the Reaction Pathway of a Non-heme Iron Oxygenase Using Ancestral Sequence Reconstruction

被引：1
|
作者：
Yang, Di [1 ,2 ]
Chiang, Chang-Hwa [1 ,2 ]
Wititsuwannakul, Taveechai [1 ]
Brooks, Charles L. [1 ,2 ,4 ]
Zimmerman, Paul M. [1 ]
Narayan, Alison R. H. [1 ,2 ,3 ]
机构：
[1] Department of Chemistry, University of Michigan, Ann Arbor,MI,48109, United States
[2] Life Science Institute, University of Michigan, Ann Arbor,MI,48109, United States
[3] Program in Chemical Biology, University of Michigan, Ann Arbor,MI,48109, United States
[4] Enhanced Program in Biophysics, University of Michigan, Ann Arbor,MI,48109, United States
来源：
Journal of the American Chemical Society | 2024年 / 146卷 / 50期
关键词：
Hydrogen bonds;
D O I：
10.1021/jacs.4c08420
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：34352 / 34363
相关论文
共 50 条
  • [1] The archaeal non-heme iron-containing Sulfur Oxygenase Reductase
    Ferreira, P.
    Fernandes, P. A.
    Ramos, M. J.
    COORDINATION CHEMISTRY REVIEWS, 2022, 455
  • [2] CloR, a bifunctional non-heme iron oxygenase involved in clorobiocin biosynthesis
    Pojer, F
    Kahlich, R
    Kammerer, B
    Li, SM
    Heide, L
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (33) : 30661 - 30668
  • [3] Reaction mechanisms of mononuclear non-heme iron oxygenases
    Abu-Omar, MM
    Loaiza, A
    Hontzeas, N
    CHEMICAL REVIEWS, 2005, 105 (06) : 2227 - 2252
  • [4] Non-heme induction of heme oxygenase-1 does not alter cellular iron metabolism
    Sheftel, Alex D.
    Kim, Sangwon F.
    Ponka, Prem
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (14) : 10480 - 10486
  • [5] Divergent non-heme iron enzymes in the nogalamycin biosynthetic pathway
    Siitonen, Vilja
    Selvaraj, Brinda
    Niiranen, Laila
    Lindqvist, Ylva
    Schneider, Gunter
    Metsa-Ketela, Mikko
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 113 (19) : 5251 - 5256
  • [6] Mechanistic Investigation of Methylphosphonate Synthase, a Non-Heme Iron-Dependent Oxygenase
    Cooke, Heather A.
    Peck, Spencer C.
    Evans, Bradley S.
    van der Donk, Wilfred A.
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (38) : 15660 - 15663
  • [7] Non-heme iron oxygenases
    Ryle, MJ
    Hausinger, RP
    CURRENT OPINION IN CHEMICAL BIOLOGY, 2002, 6 (02) : 193 - 201
  • [8] NON-HEME IRON PROTEINS
    SMITH, MH
    NATURE, 1966, 210 (5034) : 341 - &
  • [9] Amino acid iron chelate is absorbed by the non-heme iron pathway.
    Pizarro, F
    Olivares, M
    Mazariegos, D
    Arredondo, M
    Hertrampf, E
    PEDIATRIC RESEARCH, 2002, 52 (03)
  • [10] Heme and non-heme iron in oxygenases.
    Groves, JT
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 229 : U1077 - U1077
12345