Research optical interferometer biosensor based on porous silicon

被引：0

作者：

Li, Rui ^{[1
]}

Tu, Yi-Xian ^{[4
]}

Li, Chen-Chen ^{[4
]}

Lv, Xiao-Yi ^{[2
]}

Jia, Zhen-Hong ^{[3
]}

Zhang, Fu-Chun ^{[4
]}

机构：

[1] School of Physics, Xinjiang University, Urumqi 830046, China

[2] School of Electronic and Information Engineer, Xi'an Jiaotong University, Xi'an 710049, China

[3] College of Information Science and Engineering, Xinjiang University, Urumqi 830046, China

[4] Key Laboratory of Xinjiang Biological Resources and Gene Engineering, College of Life Sciences and Technology, Xinjiang University, Urumqi 830046, China

来源：

Guangdianzi Jiguang/Journal of Optoelectronics Laser | 2010年 / 21卷 / 07期

关键词：

Biosensors - Doppler effect - Antibodies - Antigens - Fourier transforms - Silicon compounds;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The micro-porous silicon is prepared as sensor support material, and the Si-OH band at the surface is formed by the immersion method of hydrogen peroxide. Porous silicon is functionalized by using oxidation and silanization, then Ang-II antibody with different concentration are immobilized to the porous surface by glutaraldehyde. The changes of Fourier transformation infrared spectrum and reflect spectrum before and after antigen-antibody reaction are observed. The results show that silanization effect is obvious. After antigen-antibody reaction, the reflection spectrum has a red shift, and the red shift of spectrum increases with the increase of antibody concentration, and presents a nonlinear relationship.

引用

页码：1111 / 1114

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