Prothymosin-α mediates nuclear import of the INrf2/ Cul3Rbx1 complex to degrade nuclear Nrf2

被引：0
|
作者：
Niture, Suryakant K. [1 ]
Jaiswal, Anil K. [1 ]
机构：
[1] Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, 655 West Baltimore St., Baltimore, MD 21201, United States
来源：
Journal of Biological Chemistry | 2009年 / 284卷 / 20期
关键词：
All Open Access; Hybrid Gold; Green;
D O I：
10.1074/jbc.M808084200
中图分类号：
学科分类号：
摘要：
22
引用
收藏
页码：13856 / 13868
相关论文
共 50 条
  • [21] RETRACTED: Hsp90 Interaction with INrf2(Keap1) Mediates Stress-induced Nrf2 Activation (Retracted article. See vol. 289, pg. 11568, 2014)
    Niture, Suryakant K.
    Jaiswal, Anil K.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (47) : 36865 - 36875
  • [22] RETRACTED: Inhibitor of Nrf2 (INrf2 or Keap1) Protein Degrades Bcl-xL via Phosphoglycerate Mutase 5 and Controls Cellular Apoptosis (Retracted Article)
    Niture, Suryakant K.
    Jaiswal, Anil K.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (52) : 44542 - 44556
  • [23] Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer
    Martinez, Victor D.
    Vucic, Emily A.
    Pikor, Larissa A.
    Thu, Kelsie L.
    Hubaux, Roland
    Lam, Wan L.
    MOLECULAR CANCER, 2013, 12
  • [24] Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer
    Victor D Martinez
    Emily A Vucic
    Larissa A Pikor
    Kelsie L Thu
    Roland Hubaux
    Wan L Lam
    Molecular Cancer, 12
  • [25] Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop via NRF2 in cancer therapeutic resistance
    Hong Wang
    Qianqian Wang
    Guodi Cai
    Zhijian Duan
    Zoann Nugent
    Jie Huang
    Jianwei Zheng
    Alexander D.Borowsky
    Jian Jian Li
    Peiqing Liu
    Hsing-Jien Kung
    Leigh Murphy
    Hong-Wu Chen
    Junjian Wang
    Acta Pharmaceutica Sinica B, 2022, 12 (04) : 1871 - 1884
  • [26] Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop via NRF2 in cancer therapeutic resistance
    Wang, Hong
    Wang, Qianqian
    Cai, Guodi
    Duan, Zhijian
    Nugent, Zoann
    Huang, Jie
    Zheng, Jianwei
    Borowsky, Alexander D.
    Li, Jian Jian
    Liu, Peiqing
    Kung, Hsing-Jien
    Murphy, Leigh
    Chen, Hong-Wu
    Wang, Junjian
    ACTA PHARMACEUTICA SINICA B, 2022, 12 (04) : 1871 - 1884
  • [27] Arkadia mediates sumoylation-dependent degradation of Nrf2 in promyelocytic leukemia-nuclear bodies
    McIntosh, Deneshia
    Arinze, Ifeanyi
    FASEB JOURNAL, 2014, 28 (01):
  • [28] Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression
    Bloom, DA
    Jaiswal, AK
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (45) : 44675 - 44682
  • [29] RETRACTION: Aromatase Inhibitor-mediated Downregulation of INrf2 (Keap1) Leads to Increased Nrf2 and Resistance in Breast Cancer (Retraction of Vol 14, Pg 1728, 2015)
    Khatri, Raju
    Shah, Preeti
    Guha, Rupa
    Rassool, Feyruz V.
    Tomkinson, Alan E.
    Brodie, Angela
    Jaiswal, Anil K.
    MOLECULAR CANCER THERAPEUTICS, 2018, 17 (11) : 2491 - 2491
  • [30] Sodium fluoride generates ROS and alters transcription of genes for xenobiotic metabolizing enzymes in adult zebrafish (Danio rerio) liver: expression pattern of Nrf2/Keap1 (INrf2)
    Mukhopadhyay, Debdip
    Srivastava, Ritu
    Chattopadhyay, Ansuman
    TOXICOLOGY MECHANISMS AND METHODS, 2015, 25 (05) : 364 - 373
12345