Metal-free construction of diverse 1,2,4-triazolo[1,5-a]pyridines on water

被引：0

作者：

Chunhua Ma ^{[1
]}

Mengjiao Liu ^{[1
]}

Siyu Ouyang ^{[1
]}

Zhenwei Cui ^{[2
]}

Jingjing Bi ^{[1
]}

Yuqin Jiang ^{[1
]}

Zhiguo Zhang ^{[1
]}

机构：

[1] Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals, Key Laboratory of Green Chemical Media and Reactions,Ministry of Education, Henan Engineering Research Centre of Chiral Hydroxyl Pharmaceutical, Henan Engineering

[2] Chongqing Aoshe Bio-chemical

来源：

Chinese Chemical Letters | 2025年 / 36卷 / 01期

关键词：

D O I：

暂无

中图分类号：

O626.32 [氮杂苯（吡啶）族];

学科分类号：

摘要：

A transition-metal-and oxidant-free amination/cyclization reaction to access 1,2,4-triazolo[1,5-a]pyridines was realized in water by using amino diphenylphosphinate as amino source. A broad array of readily accessible N-(pyridyl)amides could be converted into the products featuring a diverse set of functional groups. The sustainable methodology was successfully applied to the late-stage functionalization of natural products and drugs.

引用

页码：273 / 276

页数：4

共 50 条

[21] NEW HERBICIDAL DERIVATIVES OF 1,2,4-TRIAZOLO[1,5-A] PYRIMIDINE
KLESCHICK, WA
COSTALES, MJ
DUNBAR, JE
MEIKLE, RW
MONTE, WT
PEARSON, NR
SNIDER, SW
VINOGRADOFF, AP
PESTICIDE SCIENCE, 1990, 29 (03): : 341 - 355
[22] Recent advances in 1,2,4-triazolo[1,5-a]pyrimidine chemistry
Fischer, Gunther
ADVANCES IN HETEROCYCLIC CHEMISTRY, VOL 128, 2019, 128 : 1 - 101
[23] Recent Progress in 1,2,4-Triazolo[1,5-a]pyrimidine Chemistry
Fischer, Gunther
ADVANCES IN HETEROCYCLIC CHEMISTRY, VOL 95, 2008, 95 : 143 - 219
[24] TRICYCLIC HETEROAROMATIC SYSTEMS - 1,2,4-TRIAZOLO[1,5-A]QUINOXALINE
CATARZI, D
CECCHI, L
COLOTTA, V
FILACCHIONI, G
MELANI, F
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1992, 29 (05) : 1161 - 1163
[25] Synthesis and antitumor activities of 2-(substituted)phenyl-1,2,4-triazolo[1,5-a]pyridines
Zhang, Guolin
Hu, Yongzhou
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2007, 44 (04) : 919 - 922
[26] PhI(OCOCF3)2-Mediated Intramolecular Oxidative N-N Bond Formation: Metal-Free Synthesis of 1,2,4-Triazolo[1,5-a]pyridines
Zheng, Zisheng
Ma, Shuangyu
Tang, Linlin
Zhang-Negrerie, Daisy
Du, Yunfei
Zhao, Kang
JOURNAL OF ORGANIC CHEMISTRY, 2014, 79 (10): : 4687 - 4693
[27] Studies with polyfunctionally substituted heteroaromatics: New routes for the synthesis of polyfunctionally substituted pyridines and 1,2,4-triazolo[1,5-a]pyridines
AlOmran, F
Khalik, MMA
Elnagdi, MH
HETEROATOM CHEMISTRY, 1995, 6 (06) : 545 - 551
[28] SYNTHESIS OF 1,2,4-TRIAZOLO[1,5-A]PYRIMIDINE-2-SULFONAMIDES
SHANKAR, RB
PEWS, RG
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1993, 30 (01) : 169 - 172
[29] SYNTHESIS OF DIHYDRO-1,2,4-TRIAZOLO[1,5-A]PYRIMIDINES
WERMANN, K
HARTMANN, M
SYNTHESIS-STUTTGART, 1991, (03): : 189 - 191
[30] REACTIONS OF AMINO-1,2,4-TRIAZOLO[1,5-A]-PYRIMIDINE AND HYDRAZINO-1,2,4-TRIAZOLO[1,5-A]-PYRIMIDINE DERIVATIVES WITH DMF DMA .8.
HEMPEL, U
LIPPMANN, E
TENOR, E
ZEITSCHRIFT FUR CHEMIE, 1990, 30 (09): : 320 - 321

← 1 2 3 4 5 →