Trifluoromethyl-substituted pyridines through displacement of iodine by in situ generated (trifluoromethyl)copper

被引：0

作者：

Cottet, Fabrice ^{[1
]}

Schlosser, Manfred ^{[1
]}

机构：

[1] Section de Chimie (BCh), Universite, 1015 Lausanne, Switzerland

来源：

European Journal of Inorganic Chemistry | 2002年 / 02期

关键词：

Copper; -; Iodine; Nitrogen; Pyridine;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

A literature method reported for iodobenzene and congeners was successfully extended to the pyridine series. 2-Iodopyridines can be converted into 2-(trifluoromethyl)pyridines almost quantitatively. In contrast, yields ore moderate at best if 3- and 4-iodopyridines or 2-bromopyridines are used as the starting materials.

引用

页码：327 / 330

共 50 条

[31] Synthesis and transformations of trifluoromethyl-substituted cyanopyrrolines
A. Yu. Volkonskii
N. D. Kagramanov
Russian Chemical Bulletin, 2023, 72 : 1560 - 1568
[32] Trifluoromethyl-substituted DI- and tetrahydroazolopyrimidines
Desenko S.M.
Gladkov E.S.
Nenaidenko V.G.
Shishkin O.V.
Shishkina S.V.
Chemistry of Heterocyclic Compounds, 2004, 40 (1) : 65 - 69
[33] Trifluoromethyl-substituted imidazolines: Novel precursors of trifluoromethyl ketones amenable to peptide synthesis
J Am Chem Soc, 35 (8485):
[34] Trifluoromethyl-substituted imidazolines: Novel precursors of trifluoromethyl ketones amenable to peptide synthesis
Derstine, CW
Smith, DN
Katzenellenbogen, JA
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (35) : 8485 - 8486
[35] General and Scalable Approach to Trifluoromethyl-Substituted Cyclopropanes
Ahunovych, Volodymyr
Klipkov, Anton A.
Bugera, Maksym
Tarasenko, Karen
Trofymchuk, Serhii
Stanko, Oleh
Boretskyi, Andrii
Zheludenko, Mykola
Sadkova, Iryna V.
Mykhailiuk, Pavel K.
JOURNAL OF ORGANIC CHEMISTRY, 2023, 88 (06): : 3859 - 3870
[36] DEACYLATION RATES OF SEVERAL TRIFLUOROMETHYL-SUBSTITUTED ACYLCHYMOTRYPSINS
ENRIQUEZ, PM
GERIG, JT
BIOCHEMISTRY, 1969, 8 (08) : 3156 - &
[37] Conformational studies on heteroleptic trifluoromethyl-substituted phenylboranes
Samigullin, Kamil
Soltani, Yashar
Lerner, Hans-Wolfram
Wagner, Matthias
Bolte, Michael
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 2016, 72 : 189 - +
[38] Reactions of trifluoromethyl-substituted arylacetylenes with arenes in superacids
Alkhafaji, H. M. H.
Ryabukhin, D. S.
Muzalevskiy, V. M.
Osetrova, L. V.
Vasilyev, A. V.
Nenajdenko, V. G.
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2013, 49 (03) : 327 - 341
[39] TRIFLUOROMETHYL-SUBSTITUTED PYRIMIDINES FROM ENAMINES AND TRIFLUOROACETONITRILE
BURGER, K
WASSMUTH, U
HEIN, F
ROTTEGGER, S
LIEBIGS ANNALEN DER CHEMIE, 1984, (05): : 991 - 1002
[40] Convenient route to trifluoromethyl-substituted cyclopropane derivatives
Mykhailiuk, Pavel K.
Afonin, Sergii
Ulrich, Anne S.
Komarov, Igor V.
SYNTHESIS-STUTTGART, 2008, (11): : 1757 - 1760

← 1 2 3 4 5 →