A low noise and low power device composed of electrode and CD ASIC for neural and other vital signals recording

被引:0
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作者
Sun, Jianhui [1 ,2 ,3 ,4 ]
Wang, Zibin [1 ]
Wang, Tongxi [5 ]
Liu, Guozhu [6 ]
Tian, Jiangwei [7 ]
机构
[1] School of Physics and Electronics, Shandong Normal University, Jinan,250014, China
[2] State Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing,100190, China
[3] Shandong Key Laboratory of Medical Physics and Image Processing, School of Physics and Electronics, Shandong Normal University, Jinan,250014, China
[4] Center of Light Manipulations and Applications & Shandong Provincial Key Laboratory of Optics and Photonic Device, School of Physics and Electronics, Shandong Normal University, Jinan,250014, China
[5] Interuniversity Microelectronics Centre, Leuven, Belgium
[6] School of Electronic Science and Engineering, Southeast University, Nanjing,210096, China
[7] State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of TCM Evaluation and Translation Research, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing,211198, China
关键词
Nanoparticles - Electroencephalography - Signal to noise ratio - Graphene - Polypyrroles - Analog to digital conversion - Energy utilization - Application specific integrated circuits - Biomedical signal processing - Electrocardiography;
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摘要
In this paper, to effectively record the electroencephalogram (EEG) and other body-vital signals of the healthy volunteer, a low-noise and low-power device was developed. The proposed device consisted of a novel convenient, reliable and sensitive electrode realized by an Ag/AgCl dry-contact electrode coated with nano-composites and a novel post-electrode chopper digitizer (CD). The CD consisted of a low noise and low power chopping pre-amplifier with gain and band-width (BW) adjustable abilities and an intermediate speed and low power successive approximation register-analog digital converter (SAR-ADC). First, using the front-end electrode, the neural signal was received from the brain scalp; second, using the CD, the amplified analog voltage outputting from the chopping pre-amplifier was converted into digital sequences using the SAR-ADC. Testing results showed that the contact resistance between the electrode and the brain scalp was optimized to about 300.00 kΩ, as the electrode was coated with polypyrrole-graphene nano-particles. And, the linear relevancy between the electrode and the traditional wet-contact electrode was more than 93%. Finally, the CD was manufactured with CMOS technology (SmicRF180NM 1Poly6M) under a supply voltage of 1.0 V. Testing results of the CD showed that: (1) the CD achieved an inputting-referred noise of 0.40 μV root-mean-square (RMS) in 0.18–200 Hz, the energy consumption was 3.40 μW for one chopping pre-amplifier, 200 μW for SAR-ADC, etc.; (2) the SAR-ADC achieved an effective number of bits (ENOB) of 9.96-bits under conversion rate reaching 1.00 MSps, the signal noise ratio (SNR) was 60.97 dB, etc. The designed device could satisfy recording for EEG signals in μV level, also, the device could be used for detecting electrocardiography (EKG) signals in mV level. So, the low noise and low power device worked well for recording micro neural signals, and suitable for constructing reliable portable or wearable pervasive bio-devices used for multiple body-vital signals too. © 2021 Elsevier B.V.
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