TPGS-mediated one-pot synthesis, XRD structural analysis, antimicrobial evaluation and molecular docking of novel heterocycles as potential inhibitors of p53-MDM2 protein

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作者
Anand, K. [1 ,2 ]
Naicker, Tricia [3 ]
Baijnath, Sooraj [3 ]
Mphahlele, Malose J. [4 ]
Katari, Naresh Kumar [5 ]
Zamisa, Sizwe J. [6 ]
Balakumar, C. [7 ]
Vijayakumar, K. [8 ]
Palanisamy, Subramanian [9 ]
Saravanan, Muthupandian [10 ]
Boomi, P. [11 ]
Chuturgoon, Anil [1 ]
机构
[1] Discipline of Medical Biochemistry, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban,4001, South Africa
[2] Department of Chemical Pathology, School of Pathology, Faculty of Health Sciences and National Health Laboratory Service, University of the Free State, Bloemfontein, South Africa
[3] Catalysis and Peptide Research Unit, University of KwaZulu Natal, Durban, South Africa
[4] Department of Chemistry, College of Science, Engineering and Technology, University of South Africa, Private Bag X6, Florida,1710, South Africa
[5] Department of Chemistry, GITAM deemed to be University, Hyderabad,Telangana,502329, India
[6] School of Chemistry and Physics, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban,4000, South Africa
[7] Faculty of Pharmacy, Philadelphia University, Philadelphia University, P. O. Box - 1, 19392, Jordan
[8] Department of Chemistry, M. Kumarasamy College of Engineering, Karur,Tamilnadu,639 113, India
[9] East Coast Life Sciences Institute, Gangneung-Wonju National University, 120 Gangneung, Gangwon,210-720, Korea, Republic of
[10] Department of Microbiology and Immunology, Division of Biomedical Sciences, School of Medicine, College of Health Sciences, Mekelle University, Mekelle,1871, Ethiopia
[11] Department of Bioinformatics, Alagappa University, Karaikudi,630 003, India
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