TPGS-mediated one-pot synthesis, XRD structural analysis, antimicrobial evaluation and molecular docking of novel heterocycles as potential inhibitors of p53-MDM2 protein

被引：0

作者：

Anand, K. ^{[1
,2
]}

Naicker, Tricia ^{[3
]}

Baijnath, Sooraj ^{[3
]}

Mphahlele, Malose J. ^{[4
]}

Katari, Naresh Kumar ^{[5
]}

Zamisa, Sizwe J. ^{[6
]}

Balakumar, C. ^{[7
]}

Vijayakumar, K. ^{[8
]}

Palanisamy, Subramanian ^{[9
]}

Saravanan, Muthupandian ^{[10
]}

Boomi, P. ^{[11
]}

Chuturgoon, Anil ^{[1
]}

机构：

[1] Discipline of Medical Biochemistry, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban,4001, South Africa

[2] Department of Chemical Pathology, School of Pathology, Faculty of Health Sciences and National Health Laboratory Service, University of the Free State, Bloemfontein, South Africa

[3] Catalysis and Peptide Research Unit, University of KwaZulu Natal, Durban, South Africa

[4] Department of Chemistry, College of Science, Engineering and Technology, University of South Africa, Private Bag X6, Florida,1710, South Africa

[5] Department of Chemistry, GITAM deemed to be University, Hyderabad,Telangana,502329, India

[6] School of Chemistry and Physics, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban,4000, South Africa

[7] Faculty of Pharmacy, Philadelphia University, Philadelphia University, P. O. Box - 1, 19392, Jordan

[8] Department of Chemistry, M. Kumarasamy College of Engineering, Karur,Tamilnadu,639 113, India

[9] East Coast Life Sciences Institute, Gangneung-Wonju National University, 120 Gangneung, Gangwon,210-720, Korea, Republic of

[10] Department of Microbiology and Immunology, Division of Biomedical Sciences, School of Medicine, College of Health Sciences, Mekelle University, Mekelle,1871, Ethiopia

[11] Department of Bioinformatics, Alagappa University, Karaikudi,630 003, India

来源：

Journal of Molecular Structure | 2021年 / 1202卷

关键词：

26;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 47 条

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EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 188
[22] 2,4,5-Tris(alkoxyaryl)imidazoline derivatives as potent scaffold for novel p53-MDM2 interaction inhibitors: Design, synthesis, and biological evaluation
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[23] Design, synthesis and biological evaluation of novel 3,4,5-trisubstituted aminothiophenes as inhibitors of p53-MDM2 interaction. Part 1
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[24] Design, synthesis, and biological evaluation of furan-bearing pyrazolo[3,4-b]pyridines as novel inhibitors of CDK2 and P53-MDM2 protein-protein interaction
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[25] New chemical tools for disrupting the MDM2/p53 protein-protein interaction: Identification, synthesis and biological evaluation of a novel class of MDM2/p53 inhibitors
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[26] One-pot synthesis, molecular docking, ADMET, and DFT studies of novel pyrazolines as promising SARS-CoV-2 main protease inhibitors
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[27] One-pot synthesis, molecular docking, ADMET, and DFT studies of novel pyrazolines as promising SARS-CoV-2 main protease inhibitors
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[28] One-pot strategy for thiazole tethered 7-ethoxy quinoline hybrids: Synthesis and potential antimicrobial agents as dihydrofolate reductase (DHFR) inhibitors with molecular docking study
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[29] Design, one-pot synthesis, in silico ADMET prediction and molecular docking of novel triazolyl thiadiazine and thiazole derivatives with evaluation of antimicrobial, antioxidant and antibiofilm inhibition activity
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[30] Design, one-pot synthesis, in silico ADMET prediction and molecular docking of novel triazolyl thiadiazine and thiazole derivatives with evaluation of antimicrobial, antioxidant and antibiofilm inhibition activity
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