TPGS-mediated one-pot synthesis, XRD structural analysis, antimicrobial evaluation and molecular docking of novel heterocycles as potential inhibitors of p53-MDM2 protein

被引：0

作者：

Anand, K. ^{[1
,2
]}

Naicker, Tricia ^{[3
]}

Baijnath, Sooraj ^{[3
]}

Mphahlele, Malose J. ^{[4
]}

Katari, Naresh Kumar ^{[5
]}

Zamisa, Sizwe J. ^{[6
]}

Balakumar, C. ^{[7
]}

Vijayakumar, K. ^{[8
]}

Palanisamy, Subramanian ^{[9
]}

Saravanan, Muthupandian ^{[10
]}

Boomi, P. ^{[11
]}

Chuturgoon, Anil ^{[1
]}

机构：

[1] Discipline of Medical Biochemistry, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban,4001, South Africa

[2] Department of Chemical Pathology, School of Pathology, Faculty of Health Sciences and National Health Laboratory Service, University of the Free State, Bloemfontein, South Africa

[3] Catalysis and Peptide Research Unit, University of KwaZulu Natal, Durban, South Africa

[4] Department of Chemistry, College of Science, Engineering and Technology, University of South Africa, Private Bag X6, Florida,1710, South Africa

[5] Department of Chemistry, GITAM deemed to be University, Hyderabad,Telangana,502329, India

[6] School of Chemistry and Physics, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban,4000, South Africa

[7] Faculty of Pharmacy, Philadelphia University, Philadelphia University, P. O. Box - 1, 19392, Jordan

[8] Department of Chemistry, M. Kumarasamy College of Engineering, Karur,Tamilnadu,639 113, India

[9] East Coast Life Sciences Institute, Gangneung-Wonju National University, 120 Gangneung, Gangwon,210-720, Korea, Republic of

[10] Department of Microbiology and Immunology, Division of Biomedical Sciences, School of Medicine, College of Health Sciences, Mekelle University, Mekelle,1871, Ethiopia

[11] Department of Bioinformatics, Alagappa University, Karaikudi,630 003, India

来源：

Journal of Molecular Structure | 2021年 / 1202卷

关键词：

26;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 47 条

[1] TPGS-mediated one-pot synthesis, XRD structural analysis, antimicrobial evaluation and molecular docking of novel heterocycles as potential inhibitors of p53-MDM2 protein
Anand, K.
Naicker, Tricia
Baijnath, Sooraj
Mphahlele, Malose J.
Katari, Naresh Kumar
Zamisa, Sizwe J.
Balakumar, C.
Vijayakumar, K.
Palanisamy, Subramanian
Saravanan, Muthupandian
Boomi, P.
Chuturgoon, Anil
JOURNAL OF MOLECULAR STRUCTURE, 2020, 1202
[2] Insight on Heterocycles as p53-MDM2 Protein-Protein Interaction Inhibitors: Molecular Mechanism for p53 Activation
Basha, N. Jeelan
Mohan, R. M.
CHEMISTRYSELECT, 2024, 9 (10):
[3] Synthesis and evaluation of novel orally active p53-MDM2 interaction inhibitors
Miyazaki, Masaki
Naito, Hiroyuki
Sugimoto, Yuuichi
Yoshida, Keisuke
Kawato, Haruko
Okayama, Tooru
Shimizu, Hironari
Miyazaki, Masaya
Kitagawa, Mayumi
Seki, Takahiko
Fukutake, Setsuko
Shiose, Yoshinobu
Aonuma, Masashi
Soga, Tsunehiko
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 21 (14) : 4319 - 4331
[4] In Silico Screening of Inhibitors of p53-MDM2 Protein Complex through Homology Modelling and Molecular docking
Cabrera, H. S.
Medina, I. C., Jr.
Tayo, L. L.
4TH ELECTRONIC AND GREEN MATERIALS INTERNATIONAL CONFERENCE 2018 (EGM 2018), 2018, 2045
[5] Design, Synthesis and Biological Evaluation of Sulfamide and Triazole Benzodiazepines as Novel p53-MDM2 Inhibitors
Yu, Zhiliang
Zhuang, Chunlin
Wu, Yuelin
Guo, Zizhao
Li, Jin
Dong, Guoqiang
Yao, Jianzhong
Sheng, Chunquan
Miao, Zhenyuan
Zhang, Wannian
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2014, 15 (09): : 15741 - 15753
[6] Synthesis and cytotoxicity of novel dispiro derivatives of 5-arylidenoxazolones, potential inhibitors of p53-MDM2 protein-protein interaction
Beloglazkina, A. A.
Skvortsov, D. A.
Tafeenko, V. A.
Majouga, A. G.
Zyk, N. V.
Beloglazkina, E. K.
RUSSIAN CHEMICAL BULLETIN, 2018, 67 (03) : 562 - 569
[7] Discovery, Synthesis, and Biological Evaluation of Orally Active Pyrrolidone Derivatives as Novel Inhibitors of p53-MDM2 Protein-Protein Interaction
Zhuang, Chunlin
Miao, Zhenyuan
Zhu, Lingjian
Dong, Guoqiang
Guo, Zizhao
Wang, Shengzheng
Zhang, Yongqiang
Wu, Yuelin
Yao, Jianzhong
Sheng, Chunquan
Zhang, Wannian
JOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 (22) : 9630 - 9642
[8] Synthesis and biological evaluation of thio-benzodiazepines as novel small molecule inhibitors of the p53-MDM2 protein-protein interaction
Zhuang, Chunlin
Miao, Zhenyuan
Zhu, Lingjian
Zhang, Yongqiang
Guo, Zizhao
Yao, Jianzhong
Dong, Guoqiang
Wang, Shengzheng
Liu, Yang
Chen, Hai
Sheng, Chunquan
Zhang, Wannian
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 46 (11) : 5654 - 5661
[9] Design, synthesis and biological evaluation of novel pyrrolidone-based derivatives as potent p53-MDM2 inhibitors
Si, Dongjuan
Luo, Huijuan
Zhang, Xiaomeng
Yang, Kundi
Wen, Hongmei
Li, Wei
Liu, Jian
BIOORGANIC CHEMISTRY, 2021, 115
[10] Synthesis and Biological Evaluation of Novel Dispiro Compounds based on 5-Arylidenehydantoins and Isatins as Inhibitors of p53-MDM2 Protein-Protein Interaction
Beloglazkina, Anastasia
Barashkin, Alexander
Polyakov, Vladislav
Kotovsky, German
Karpov, Nikita
Mefedova, Sofia
Zagribelny, Bogdan
Ivanenkov, Yan
Kalinina, Marina
Skvortsov, Dmitry
Tafeenko, Victor
Zyk, Nikolay
Majouga, Alexander
Beloglazkina, Elena
CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2020, 56 (06) : 747 - 755

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