Research Progress on Reversing Multidrug Resistance in Tumors by Using Chinese Medicine

被引：0
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作者：
ZHAO Huandong [1 ,2 ]
XIE Hongjuan [3 ]
LI Jian [1 ]
REN Caiping [4 ]
CHEN Yuxiang [2 ]
机构：
[1] Key Laboratory of Nanobiological Technology of Chinese Ministry of Health,Xiangya Hospital,Central South University
[2] School of Pharmacy,Central South University
[3] Department of Pharmacy,Tongren Hospital,Shanghai Jiaotong University,School of Medicine
[4] Cancer Research Institute,Collaborative Innovation Center for Cancer Medicine,Key Laboratory for Carcinogenesis of Chinese Ministry of Health,School of Basic Medical Science,Central South
来源：
Chinese Journal of Integrative Medicine. | 2018年 / 24卷 / 06期
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摘要：
Multidrug resistance(MDR) is a major cause of cancer chemotherapy failure, and it is important to develop suitable reversal agents to overcome MDR. A majority of chemical reversal agents have acceptable reversal effects. However, the toxicity and adverse reactions associated with these agents restricts their clinical use. Chinese medicines(CMs) have lower toxicities and adverse reactions and are associated with multiple components, multiple targets and reduced toxicity. CMs have several advantages and could reverse MDR, decrease drug dosage, enhance patient compliance and increase efficacy. This review summarizes the current progress of CM reversal agents..
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页数：7
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