Single-cell atlas defines distinct immune escape mechanisms in colorectal cancer

被引：0
|
作者：
Chu, Xiaojing [1 ]
Zhang, Zemin
机构：
[1] Changping Lab, Beijing, Peoples R China
来源：
NATURE CANCER | 2024年 / 5卷 / 09期
关键词：
D O I：
10.1038/s43018-024-00809-x
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
An integrative single-cell analysis of the human colorectum reveals tumor-associated cellular alterations and regulatory pathways. Patient stratification based on cellular composition of the tumor microenvironment suggests distinct immune evasion mechanisms in colorectal cancer.
引用
收藏
页码：1292 / 1293
页数：2
相关论文
共 50 条
  • [31] Multiregion single-cell sequencing reveals the transcriptional landscape of the immune microenvironment of colorectal cancer
    Wang, Wei
    Zhong, Yu
    Zhuang, Zhenkun
    Xie, Jiarui
    Lu, Yueer
    Huang, Chengzhi
    Sun, Yan
    Wu, Liang
    Yin, Jianhua
    Yu, Hang
    Jiang, Zhiqiang
    Wang, Shanshan
    Wang, Chunqing
    Zhang, Yuanhang
    Huang, Yilin
    Han, Chongyin
    Zhong, Zhenggang
    Hu, Jialin
    Ouyang, Ying
    Liu, Huisheng
    Yu, Mengya
    Wei, Xiaochan
    Chen, Dandan
    Huang, Lizhen
    Hou, Yong
    Lin, Zhanglin
    Liu, Shiping
    Ling, Fei
    Yao, Xueqing
    CLINICAL AND TRANSLATIONAL MEDICINE, 2021, 11 (01):
  • [32] Implications of single-cell immune landscape of tumor microenvironment for the colorectal cancer diagnostics and therapy
    Ahmad Alzamami
    Medical Oncology, 40
  • [33] Single-cell and bulk characterisation of the distinct immune landscape and possible regulatory mechanisms in coronary plaques vulnerability
    Liang, Bo
    Liang, Wei-Lin
    Liao, Hui-Ling
    CLINICAL AND TRANSLATIONAL MEDICINE, 2023, 13 (06):
  • [34] A single-cell atlas of tumor microenvironment defines the continuum of gastric adenocarcinoma tumorigenesis and progression.
    Wang, Ruiping
    Song, Shumei
    Qin, Jiangjiang
    Li, Yuan
    Fan, Yibo
    Chatterjee, Deyali
    Tatlonghari, Ghia
    Xu, Zhiyuan
    Hu, Can
    Mo, Shaowei
    Sewastjanow, Matheus D.
    Abdelhakeem, Ahmed Adel Fouad
    Wang, Zhenning
    Cheng, Xiangdong
    Ajani, Jaffer A.
    Wang, Linghua
    CANCER RESEARCH, 2022, 82 (12)
  • [35] Single-cell proteomics defines the cellular heterogeneity of localized prostate cancer
    Roditi, Laura De Vargas
    Jacobs, Andrea
    Rueschoff, Jan H.
    Bankhead, Pete
    Chevrier, Stephane
    Jackson, Hartland W.
    Hermanns, Thomas
    Fankhauser, Christian D.
    Poyet, Cedric
    Chun, Felix
    Rupp, Niels J.
    Tschaebunin, Alexandra
    Bodenmiller, Bernd
    Wild, Peter J.
    CELL REPORTS MEDICINE, 2022, 3 (04)
  • [36] Immune Escape Mechanisms in Non Small Cell Lung Cancer
    Anichini, Andrea
    Perotti, Valentina E.
    Sgambelluri, Francesco
    Mortarini, Roberta
    CANCERS, 2020, 12 (12) : 1 - 20
  • [37] Mechanisms of immune escape in the cancer immune cycle
    Tang, Sha
    Ning, Qian
    Yang, Ling
    Mo, Zhongcheng
    Tang, Shengsong
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2020, 86
  • [38] Single-cell penile cancer atlas to identify disease drivers
    Masone, Maria Chiara
    NATURE REVIEWS UROLOGY, 2024, 21 (07) : 390 - 390
  • [39] A transcriptome atlas of the mouse iris at single-cell resolution defines cell types and the genomic response to pupil dilation
    Wang, Jie
    Rattner, Amir
    Nathans, Jeremy
    ELIFE, 2021, 10
  • [40] Spatial and single-cell transcriptomic analysis reveals fibroblasts dependent immune environment in colorectal cancer
    Jia, Hang
    Liu, Xianglin
    Wang, Guimin
    Yu, Yue
    Wang, Ning
    Zhang, Tianshuai
    Hao, Liqiang
    Zhang, Wei
    Yu, Guanyu
    BIOFACTORS, 2025, 51 (02)
12345