Transition-metal-free synthesis of triarylmethanes via Friedel-Crafts reactions of imidazo[1,2-a]pyridines with chlorohydrocarbon derivatives

被引：1

作者：

Fu, Xinlei ^{[1
]}

Wu, Longhui ^{[1
]}

Guo, Xiaohua ^{[1
]}

Yang, Kai ^{[1
]}

Liu, Zhaowen ^{[1
]}

机构：

[1] Gannan Med Univ, Coll Pharm, Ganzhou 341000, Jiangxi, Peoples R China

来源：

JOURNAL OF SAUDI CHEMICAL SOCIETY | 2024年 / 28卷 / 04期

关键词：

HFIP; Friedel-Crafts reactions; Imidazo[1; 2-a]pyridines; Triarylmethanes; Chlorohydrocarbon; ARYL; ALCOHOLS;

D O I：

10.1016/j.jscs.2024.101883

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile, transition-metal-free, HFIP-promoted method for the synthesis of triarylmethanes through direct Friedel-Crafts reactions of imidazo[1,2-a]pyridines with chlorohydrocarbon derivatives has been described, which allows for efficient synthesis of triarylmethanes containing imidazo[1,2-a]pyridines in good to satisfactory yields at room temperature. This transformation features simple operation, excellent functional group tolerance, and a broad substrate scope.

引用

页数：9

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