Transition-metal-free synthesis of triarylmethanes via Friedel-Crafts reactions of imidazo[1,2-a]pyridines with chlorohydrocarbon derivatives

被引：1
|
作者：
Fu, Xinlei [1 ]
Wu, Longhui [1 ]
Guo, Xiaohua [1 ]
Yang, Kai [1 ]
Liu, Zhaowen [1 ]
机构：
[1] Gannan Med Univ, Coll Pharm, Ganzhou 341000, Jiangxi, Peoples R China
来源：
JOURNAL OF SAUDI CHEMICAL SOCIETY | 2024年 / 28卷 / 04期
关键词：
HFIP; Friedel-Crafts reactions; Imidazo[1; 2-a]pyridines; Triarylmethanes; Chlorohydrocarbon; ARYL; ALCOHOLS;
D O I：
10.1016/j.jscs.2024.101883
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A facile, transition-metal-free, HFIP-promoted method for the synthesis of triarylmethanes through direct Friedel-Crafts reactions of imidazo[1,2-a]pyridines with chlorohydrocarbon derivatives has been described, which allows for efficient synthesis of triarylmethanes containing imidazo[1,2-a]pyridines in good to satisfactory yields at room temperature. This transformation features simple operation, excellent functional group tolerance, and a broad substrate scope.
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页数：9
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