CD19 CAR-T Cell Therapy: High Efficacy in Autoimmune Diseases

被引:0
|
作者
Brudermanns, Britta
机构
关键词
D O I
10.1055/a-2313-4535
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The treatment of autoimmune diseases such as systemic lupus erythematosus (SLE), idiopathic inflammatory myopathies and systemic sclerosis often requires long-term immunosuppression. F. M & uuml;ller and colleagues now investigated the resetting of aberrant autoimmunity by deep depletion of B cells as a potential strategy to achieve a sustained drug-free remission.
引用
收藏
页码:126 / 126
页数:1
相关论文
共 50 条
  • [31] BsAbs before CD19 CAR-T full ahead!
    Riedell, Peter A.
    BLOOD, 2024, 144 (03) : 249 - 251
  • [32] Anti-tumor Efficacy of CD19 CAR-T in a Raji B Cell Xenografted Mouse Model
    Xiao, Qian
    Su, Xiaolei
    BIO-PROTOCOL, 2023, 13 (08):
  • [33] ALLOGENEIC CD19 CAR EBV T CELLS FOR THE TREATMENT OF B-CELL DRIVEN AUTOIMMUNE DISEASES
    Brito, A.
    Habibi, A.
    Cha, S.
    Charbonneau, M.
    Foubert, P.
    Pham, C. D.
    Nguyen, C.
    CYTOTHERAPY, 2024, 26 (06) : E23 - E23
  • [34] Patterns and Safety of Glucocorticosteroids Use Following CD19 CAR-T Cell Therapy for B- Cell Lymphoma
    Luttwak, Efrat
    Flynn, Jessica R.
    Devlin, Sean M.
    Cassanello, Giulio
    Corona, Magdalena
    Dahi, Parastoo B.
    De Abia, Alejandro Luna
    Fein, Joshua
    Giralt, Sergio A.
    Landego, Ivan
    Lin, Richard J.
    Palomba, Maria Lia
    Parascondola, Allison
    Park, Jae H.
    Saldia, Amethyst
    Scordo, Michael
    Tomas, Ana Alarcon
    Shah, Gunjan L.
    Perales, Miguel-Angel
    Salles, Gilles
    Shouval, Roni
    BLOOD, 2023, 142
  • [35] Infectious complications among CD19 CAR-T cell therapy recipients: A single-center experience
    Walker, Bryan
    Zimmer, Andrea J.
    Stohs, Erica J.
    Lunning, Matthew
    Lyden, Elizabeth
    Abbas, Anum
    TRANSPLANT INFECTIOUS DISEASE, 2023, 25
  • [36] Should CD19 CAR-T Cells for ALL be Followed by Allogeneic Stem Cell
    Ramos, Carlos A.
    TRANSPLANTATION AND CELLULAR THERAPY, 2022, 28 (01): : 1 - 2
  • [37] Infectious complications among CD19 CAR-T cell therapy recipients: A single-center experience
    Walker, Bryan
    Zimmer, Andrea J.
    Stohs, Erica J.
    Lunning, Matthew
    Lyden, Elizabeth
    Abbas, Anum
    TRANSPLANT INFECTIOUS DISEASE, 2023, 25
  • [38] Reduced ABO blood group antibody titers in patients after CD19 CAR-T cell therapy
    Li, Qiang
    Yang, Zhihuan
    Fang, Kuo
    Wei, Shuning
    Sun, Jiali
    Liu, Wei
    Chen, Xiaojuan
    Huang, Wenyang
    Zhang, Guangji
    Shi, Yin
    Liu, Yuntao
    Gong, Xiaoyuan
    Liu, Fang
    Zhou, Xueli
    Wang, Jianxiang
    Wang, Ying
    BLOOD SCIENCE, 2023, 5 (01): : 62 - 65
  • [39] Tandem CD19/CD22 Dual Targets CAR-T Cells Therapy Obtains Superior CR Rate Than Single CD19 CAR-T Cells Infusion As Well As Sequential CD19 and CD22 CAR-T Cells Infusion for Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia Patients
    Liu, Sining
    Zhang, Xinyue
    Dai, Haiping
    Cui, Qingya
    Cui, Wei
    Yin, Jia
    Li, Zheng
    Xue, Shengli
    Yang, Chunxiu
    Yang, Xiao
    Qiu, Huiying
    Miao, Miao
    Chen, Suning
    Jin, Zhengming
    Fu, Chengcheng
    Li, Caixia
    Sun, Aining
    Han, Yue
    Wang, Ying
    Yu, Lei
    Wu, Depei
    Tang, Xiaowen
    BLOOD, 2021, 138
  • [40] Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy
    Sheih, Alyssa
    Voillet, Valentin
    Hanafi, Laila-Aicha
    DeBerg, Hannah A.
    Yajima, Masanao
    Hawkins, Reed
    Gersuk, Vivian
    Riddell, Stanley R.
    Maloney, David G.
    Wohlfahrt, Martin E.
    Pande, Dnyanada
    Enstrom, Mark R.
    Kiem, Hans-Peter
    Adair, Jennifer E.
    Gottardo, Raphael
    Linsley, Peter S.
    Turtle, Cameron J.
    NATURE COMMUNICATIONS, 2020, 11 (01)