Development of in vitro biopharmaceutics tools for predicting the bioavailability of subcutaneously injected monoclonal antibodies and oligonucleotides

被引：0
|
作者：
Somby, Karin [1 ,2 ]
Campagna, Valerio [2 ]
Sanchez-Felix, Manuel V. [3 ,4 ]
Forbes, Ben [1 ]
Vllasaliu, Driton [1 ]
机构：
[1] Kings Coll London, Inst Pharmaceut Sci, Franklin Wilkins Bldg,150 Stamford St, London SE1 9NH, England
[2] Novartis Pharm AG, Basel, Switzerland
[3] Novartis Pharm AG, Cambridge, MA USA
[4] Halozyme Therapeut, San Diego, CA USA
来源：
EXPERT OPINION ON DRUG DELIVERY | 2024年 / 21卷 / 09期
关键词：
SiRNA; GalNAc; mAbs; Biologics; Absorption; Pharmacokinetics; Physiologically based biopharmaceutics modeling (PBBM); SCISSOR; MODEL;
D O I：
10.1080/17425247.2024.2403469
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：1307 / 1310
页数：4
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