Evaluating the efficacy of immunotherapy in gastric cancer: Insights from immune checkpoint inhibitors

被引:0
|
作者
Yang, Yu-Nuo [1 ]
Wang, Li-Sheng [2 ]
Dang, Yan-Qi [1 ]
Ji, Guang [1 ]
机构
[1] Shanghai Univ Tradit Chinese Med, Longhua Hosp, Inst Digest Dis, China Canada Ctr Res Digest Dis, 725 South Wanping Rd, Shanghai 200032, Peoples R China
[2] Univ Ottawa, Dept Biochem, Ottawa, ON K1H 8M5, Canada
关键词
Gastric cancer; Immune checkpoint inhibitors; Sarcopenia; Myosteatosis; Prediction model;
D O I
10.3748/wjg.v30.i32.3726
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The emergence of immunotherapy, particularly immune checkpoint inhibitors (ICIs), represents a groundbreaking approach to treating gastric cancer (GC). However, the prognosis of GC patients receiving ICI treatment is influenced by various factors. This manuscript identified sarcopenia and myosteatosis as inde-pendent prognostic factors impacting the outcomes of GC patients treated with ICIs. Additionally, this study introduced a visual predictive model to estimate the prognosis of GC patients. If confirmed by further studies, this observation could provide valuable insights to propel the advancement of personalized clinical medicine and the integration of precision medicine practices.
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页数:5
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