A highly specific red-emitting fluorescent probe for monitoring of Cu2+ in living cells and zebrafish

被引：0

作者：

Kong, Shuai ^{[1
]}

Zhang, Yan ^{[1
]}

Xie, Lianke ^{[1
]}

Qi, Guodong ^{[1
]}

Li, Yanping ^{[2
]}

Dai, Haitao ^{[3
]}

Qi, Qiubo ^{[1
]}

Chen, Yimin ^{[1
]}

机构：

[1] State Grid Shandong Elect Power Res Inst, Jinan 250003, Peoples R China

[2] State Grid Shandong Elect Power Co, Jinan, Peoples R China

[3] State Grid Shandong Elect Power Extrahigh Power Co, Jinan, Peoples R China

来源：

LUMINESCENCE | 2024年 / 39卷 / 09期

关键词：

bioimaging; Cu2+; fluorescent probe; seminaphthorhodafluor; SENSOR;

D O I：

10.1002/bio.4886

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A novel seminaphthorhodafluor-based fluorescent probe was designed and prepared. It exhibited an outstanding off-on fluorescence response (about 45-fold enhancement) to Cu2+ because the structure changed from a spirocyclic form to a ring-open state. It showed satisfactory detection performances for Cu2+ with fast response speed, high selectivity and anti-interference, and a low detection limit (22.9 nM) due to its long emission wavelength and off-on fluorescence response mode. This probe was also satisfactorily applied for the monitoring of Cu2+ in living cells and zebrafish.

引用

页数：6

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