Intratympanic Lidocaine as a Potent Remedy for Tinnitus in Sudden Sensorineural Hearing Loss: A Double-Blind, Randomized Clinical Trial

被引:2
|
作者
Zhang, Di [1 ]
Li, Daibo [1 ]
Chen, Ting [1 ]
Feng, Xuefei [1 ]
Zhang, Juan [1 ]
机构
[1] Meishan Municipal Peoples Hosp, Dept Otorhinolaryngol Head & Neck Surg, Dongpo Rd, Meishan 620000, Sichuan, Peoples R China
关键词
Lidocaine; Sudden sensorineural hearing loss; Tinnitus; INTRAVENOUS LIDOCAINE; DIAGNOSIS;
D O I
10.1097/MAO.0000000000004283
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
ObjectiveThis study evaluates intratympanic lidocaine's efficacy and safety for tinnitus relief in sudden sensorineural hearing loss (SSNHL) patients.MethodsIn a double-blind randomized controlled trial, 100 SSNHL patients with unilateral tinnitus received either intratympanic lidocaine or saline plus usual care. Treatment impact was assessed at 1 and 3 months using the Tinnitus Handicap Inventory, subjective visual analog scale, pure-tone audiometry.ResultsThe lidocaine group demonstrated significant tinnitus relief according to the Tinnitus Handicap Inventory and visual analog scale, without pure-tone audiometry improvement or serious adverse events throughout the study period.ConclusionIntratympanic lidocaine provides a safe, efficacious treatment option for SSNHL tinnitus. Further studies should refine the dosage and delivery parameters because of SSNHL's heterogenous nature.
引用
收藏
页码:849 / 854
页数:6
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