The Vital Role of Immunohematology in Diagnosing Paroxysmal Cold Hemoglobinuria: A Clinical Case Report

被引：0
|
作者：
Gutierrez, Willy Nava [1 ,2 ]
Cortes, Paola Villa [3 ]
Morales, Ricardo Ramirez [4 ]
Garza, Juan P. Espinoza [5 ]
Mora, Jaime E. Espinosa [6 ]
机构：
[1] Inst Seguridad & Serv Sociales Trabajadores Estado, Hematol & Oncol, Monterrey, Mexico
[2] Univ Monterrey, Hematol, Monterrey, Mexico
[3] Inst Seguridad & Serv Sociales Trabajadores Estado, Crit Care Med, Monterrey, Mexico
[4] Inst Seguridad & Serv Sociales Trabajadores Estado, Rheumatol, Monterrey, Mexico
[5] Inst Seguridad & Serv Sociales Trabajadores Estado, Pulmonol, Monterrey, Mexico
[6] Inst Seguridad & Serv Sociales Trabajadores Estado, Infect Dis, Monterrey, Mexico
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 09期
关键词：
complement-mediated hemolysis; therapeutic plasma exchange (tpe); rituximab; paroxysmal cold hemoglobinuria (pch); mexico; eculizumab; cold agglutinin disease; autoimmune vasculitis; autoimmune hemolytic anemia (aiha); anca-negative; AUTOIMMUNE HEMOLYTIC-ANEMIA;
D O I：
10.7759/cureus.69362
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Paroxysmal cold hemoglobinuria (PCH) is a rare autoimmune hemolytic anemia caused by the binding of IgG immunoglobulins to red blood cells at cold temperatures, leading to hemolysis upon rewarming. The Donath-Landsteiner test can show biphasic hemolysis, leading to diagnosis. There is no consensus, but chemoimmunotherapy with or without plasma exchange is commonly employed. We present the case of a 42-year-old male who experienced symptoms of hemolysis after cold exposure in a semi-arid, warm-climate city.
引用
收藏
页数：6
相关论文
共 50 条
  • [41] A Rare and Misdiagnosed Entity Paroxysmal Nocturnal Hemoglobinuria: A Case Report
    Pokhrel, Biraj
    Gautam, Sandesh
    Khanal, Shambhu
    Pokhrel, Nishan B.
    Shrestha, Anjan
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2021, 13 (05)
  • [42] Paroxysmal Nocturnal Hemoglobinuria and Acute Kidney Injury: A Case Report
    Sumnu, Abdullah
    Donmez, Halil
    Gursu, Meltem
    Cebeci, Egemen
    Ozturk, Savas
    Kilicarslan, Isin
    Kazancioglu, Rumeyza
    TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL, 2013, 22 (01): : 126 - 128
  • [43] Report on a patient with paroxysmal cold hemoglobinuria (vol 65, pg 165, 1996)
    Subbarayan, PR
    Shichishima, T
    Yoshida, H
    Maruyama, S
    Naiki, M
    INTERNATIONAL JOURNAL OF HEMATOLOGY, 1997, 66 (01) : 121 - 121
  • [44] SEROLOGIC PROPERTIES OF A COLD HEMOLYSIN AND AN ACID HEMOLYSIN OCCURRING IN A CASE OF SYPHILITIC PAROXYSMAL COLD HEMOGLOBINURIA
    PETERSON, ET
    WALFORD, RL
    BLOOD, 1952, 7 (11) : 1106 - 1116
  • [45] A Case of Paroxysmal Cold Hemoglobinuria Associated With SARS-CoV2 Infection
    Akgun, Y.
    Perez-Alvarez, I.
    Gibb, D.
    Scher, K.
    Pepkowitz, S.
    Klapper, E.
    TRANSFUSION, 2023, 63 : 255A - 255A
  • [46] Case report: Paroxysmal nocturnal hemoglobinuria presenting with hemorrhagic esophageal varices
    Du, Runsen
    Zheng, Lihua
    Liu, Peng
    Zhao, Yaheng
    Yang, Yan
    Zhang, Lei
    Zhao, Zengren
    FRONTIERS IN MEDICINE, 2023, 10
  • [47] PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (MARCHIAFAVA-MICHELI SYNDROME) - REPORT OF CASE
    SNELL, AM
    MATHIESON, DR
    GASTROENTEROLOGY, 1950, 15 (04) : 758 - 762
  • [48] Therapeutic challenges in pregnant women with paroxysmal nocturnal hemoglobinuria A case report
    Coelho Bastos, Juliana Marques
    Pinheiro, Patricia Leal
    Rocha, Lissa Canedo
    Bicalho, Elisa Cao
    Cazeli, Alessandra Barbosa
    Marcondes, Sibia Soraya
    Pinasco, Gustavo Carreiro
    MEDICINE, 2018, 97 (36)
  • [49] A case report of pegcetacoplan use for a pregnant woman with paroxysmal nocturnal hemoglobinuria
    Du, Wei
    Mei, Lin
    RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS, 2024, 8 (04)
  • [50] The role of flow cytometry in the diagnosis of paroxysmal nocturnal hemoglobinuria in the clinical laboratory
    Richards, Stephen J.
    Barnett, David
    CLINICS IN LABORATORY MEDICINE, 2007, 27 (03) : 577 - +
12345