The Vital Role of Immunohematology in Diagnosing Paroxysmal Cold Hemoglobinuria: A Clinical Case Report

被引：0

作者：

Gutierrez, Willy Nava ^{[1
,2
]}

Cortes, Paola Villa ^{[3
]}

Morales, Ricardo Ramirez ^{[4
]}

Garza, Juan P. Espinoza ^{[5
]}

Mora, Jaime E. Espinosa ^{[6
]}

机构：

[1] Inst Seguridad & Serv Sociales Trabajadores Estado, Hematol & Oncol, Monterrey, Mexico

[2] Univ Monterrey, Hematol, Monterrey, Mexico

[3] Inst Seguridad & Serv Sociales Trabajadores Estado, Crit Care Med, Monterrey, Mexico

[4] Inst Seguridad & Serv Sociales Trabajadores Estado, Rheumatol, Monterrey, Mexico

[5] Inst Seguridad & Serv Sociales Trabajadores Estado, Pulmonol, Monterrey, Mexico

[6] Inst Seguridad & Serv Sociales Trabajadores Estado, Infect Dis, Monterrey, Mexico

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 09期

关键词：

complement-mediated hemolysis; therapeutic plasma exchange (tpe); rituximab; paroxysmal cold hemoglobinuria (pch); mexico; eculizumab; cold agglutinin disease; autoimmune vasculitis; autoimmune hemolytic anemia (aiha); anca-negative; AUTOIMMUNE HEMOLYTIC-ANEMIA;

D O I：

10.7759/cureus.69362

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Paroxysmal cold hemoglobinuria (PCH) is a rare autoimmune hemolytic anemia caused by the binding of IgG immunoglobulins to red blood cells at cold temperatures, leading to hemolysis upon rewarming. The Donath-Landsteiner test can show biphasic hemolysis, leading to diagnosis. There is no consensus, but chemoimmunotherapy with or without plasma exchange is commonly employed. We present the case of a 42-year-old male who experienced symptoms of hemolysis after cold exposure in a semi-arid, warm-climate city.

引用

页数：6

共 50 条

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SHAH, AA
DESAI, AB
INDIAN PEDIATRICS, 1977, 14 (03): : 219 - 221
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CARSWELL, J
ELOFF, P
EDKINS, P
WILLMORE, A
SOUTH AFRICAN MEDICAL JOURNAL, 1979, 55 (22): : 891 - 892
[3] Report on a patient with paroxysmal cold hemoglobinuria
Subbarayan, PR
Shichishima, T
Yoshida, H
Maruyama, S
Naiki, M
INTERNATIONAL JOURNAL OF HEMATOLOGY, 1997, 65 (02) : 165 - 167
[4] FATAL CASE OF PAROXYSMAL COLD HEMOGLOBINURIA
VANATTA, PR
MILLER, PE
WILLIAMS, CK
TEXAS MEDICINE, 1986, 82 (04) : 39 - 41
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Woofter, AC
Parks, BS
ANNALS OF INTERNAL MEDICINE, 1938, 12 (03) : 402 - 406
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Howard, CP
Mills, ES
Townsend, SR
AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 1938, 196 (06): : 792 - 796
[7] Paroxysmal hemoglobinuria - With report of a case
Swineford, O
JOURNAL OF LABORATORY AND CLINICAL MEDICINE, 1931, 16 : 347 - 353
[8] PAROXYSMAL COLD HEMOGLOBINURIA WITH POSITIVE TREPONEMA IMMOBILIZATION TEST - REPORT OF A CASE
MILIC, N
BLOOD, 1957, 12 (10) : 907 - 912
[9] Acute paroxysmal cold hemoglobinuria upon dengue fever: A case report
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JOURNAL OF ACUTE DISEASE, 2024, 13 (03) : 121 - 124
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Leger, R. M.
Allen, J. L.
Grima, K.
Garratty, G.
TRANSFUSION, 2013, 53 : 149A - 149A

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