Analysis and simulation study of the HIV/AIDS model using the real cases

被引:5
|
作者
Meetei, Mutum Zico [1 ]
DarAssi, Mahmoud H. [2 ]
Khan, Muhammad Altaf [3 ]
Koam, Ali N. A. [1 ]
Alzahrani, Ebraheem [4 ]
Ahmadini, Abdullah Ali H. [1 ]
机构
[1] Jazan Univ, Coll Sci, Dept Math, Jazan, Saudi Arabia
[2] Princess Sumaya Univ Technol, Dept Basic Sci, Amman, Jordan
[3] Univ Free State, Fac Nat & Agr Sci, Bloemfontein, South Africa
[4] King Abdulaziz Univ, Fac Sci, Dept Math, Jeddah, Saudi Arabia
来源
PLOS ONE | 2024年 / 19卷 / 06期
关键词
NUMERICAL-SOLUTION; EPIDEMIC MODEL; STABILITY; DYNAMICS; DISEASE; SPREAD; PDE;
D O I
10.1371/journal.pone.0304735
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
We construct a model to investigate HIV/AIDS dynamics in real cases and study its mathematical analysis. The study examines the qualitative outcomes and confirms the local and global asymptotic stability of both the endemic equilibrium and the disease-free equilibrium. The model's criteria for exhibiting both local and global asymptotically stable behavior are examined. We compute the endemic equilibria and obtain the existence of a unique positive endemic equilibrium. The data is fitted to the model using the idea of nonlinear least-squares fitting. Accurate parameter values are achieved by fitting the data to the model using a 95% confidence interval. The basic reproduction number is computed using parameters that have been fitted or estimated. Sensitivity analysis is performed to discover the influential parameters that impact the reproduction number and the eradication of the disease. The results show that implementing preventive measures can reduce HIV/AIDS cases.
引用
收藏
页数:24
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