Ironing out obesity

被引：1
|
作者：
de Souza, Gabriel O. [1 ]
dos Santos, Willian O. [1 ]
Donato, Jose [1 ]
机构：
[1] Univ Sao Paulo, Inst Biomed Sci, Dept Physiol & Biophys, BR-05508000 Sao Paulo, Brazil
来源：
TRENDS IN ENDOCRINOLOGY AND METABOLISM | 2024年 / 35卷 / 06期
基金：
巴西圣保罗研究基金会;
关键词：
DONATION;
D O I：
10.1016/j.tem.2024.04.001
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Obesity is associated with dysfunctions in hypothalamic neurons that regulate metabolism, including agouti-related protein (AgRP)-expressing neurons. In a recent article, Zhang et al. demonstrated that either dietor genetically induced obesity promoted iron accumulation specifically in AgRP neurons. Preventing iron overload in AgRP neurons mitigated diet-induced obesity and related comorbidities in male mice.
引用
收藏
页码：456 / 458
页数：3
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