Tumor cell metaplastic programs and failure of T cell remodeling drive resistance and progression to frontline chemoimmunotherapy in advanced gastric cancer

被引:0
|
作者
Wright, Samuel J.
An, Minae
Min, Byung Hoon
Heo, You Jeong
Parikh, Milan
Bi, Lynn
Lee, Hyuk
Kim, Taejun
Lee, Song-Yi
Moon, Jeonghyeon
Park, Ryan J.
Strickland, Matthew R.
Park, Woong Yang
Kang, Won Ki
Kim, Kyoung-Mee
Kim, Seung Tae
Mehta, Arnav
Klempner, Samuel J.
Lee, Jeeyun
机构
关键词
D O I
10.1158/1538-7445.AM2024-6846
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
6846
引用
收藏
页数:2
相关论文
共 50 条
  • [41] Association of MARCH7 with tumor progression and T-cell infiltration in esophageal cancer
    Shivam Singh
    Arjumand Bano
    Anoop Saraya
    Prasenjit Das
    Rinu Sharma
    Medical Oncology, 40
  • [42] Association of MARCH7 with tumor progression and T-cell infiltration in esophageal cancer
    Singh, Shivam
    Bano, Arjumand
    Saraya, Anoop
    Das, Prasenjit
    Sharma, Rinu
    MEDICAL ONCOLOGY, 2022, 40 (01)
  • [43] Prognostic Value of T-Cell Density in the Tumor Center and Outer Margins in Gastric Cancer
    Soeratram, Tanya T. D.
    Biesma, Hedde D.
    Egthuijsen, Jacqueline M. P.
    Kranenbarg, Elma Meershoek-Klein
    Hartgrink, Henk H.
    van de Velde, Cornelis J. H.
    Mookhoek, Aart
    van Dijk, Erik
    Kim, Yongsoo
    Ylstra, Bauke
    van Laarhoven, Hanneke W. M.
    van Grieken, Nicole C. T.
    MODERN PATHOLOGY, 2023, 36 (09)
  • [44] CD39hi identifies an exhausted tumor-reactive CD8+T cell population associated with tumor progression in human gastric cancer
    Shen, Yang
    Qiu, Yuan
    Duan, Zhen-quan
    Li, Yu-xian
    Wang, Ying
    Zhang, Yuan-yuan
    Zhu, Bao-hang
    Yu, Xiao-hong
    Tan, Xue-ling
    Chen, Weisan
    Zhuang, Yuan
    Zou, Quan-ming
    Ma, Dai-yuan
    Peng, Liu-sheng
    PHARMACOLOGICAL RESEARCH, 2024, 202
  • [45] Chemoimmunotherapy targeting Wilms' tumor 1 (WT1)-specific cytotoxic T lymphocyte and helper T cell responses for patients with pancreatic cancer
    Koido, Shigeo
    Homma, Sadamu
    Okamoto, Masato
    Takakura, Kazuki
    Gong, Jianlin
    Sugiyama, Haruo
    Ohkusa, Toshifumi
    Tajiri, Hisao
    ONCOIMMUNOLOGY, 2014, 3 (10) : e958950 - 1
  • [46] Identification of Hypoxia-ALCAMhigh Macrophage- Exhausted T Cell Axis in Tumor Microenvironment Remodeling for Immunotherapy Resistance
    Xun, Zhenzhen
    Zhou, Huanran
    Shen, Mingyi
    Liu, Yao
    Sun, Chengcao
    Du, Yanhua
    Jiang, Zhou
    Yang, Liuqing
    Zhang, Qing
    Lin, Chunru
    Hu, Qingsong
    Ye, Youqiong
    Han, Leng
    ADVANCED SCIENCE, 2024,
  • [47] Identification of Hypoxia-ALCAMhigh Macrophage-Exhausted T Cell Axis in Tumor Microenvironment Remodeling for Immunotherapy Resistance
    Xun, Zhenzhen
    Zhou, Huanran
    Shen, Mingyi
    Liu, Yao
    Sun, Chengcao
    Du, Yanhua
    Jiang, Zhou
    Yang, Liuqing
    Zhang, Qing
    Lin, Chunru
    Hu, Qingsong
    Ye, Youqiong
    Han, Leng
    ADVANCED SCIENCE, 2024, 11 (33)
  • [48] Roles of the tumor microenvironment in the resistance to programmed cell death protein 1 inhibitors in patients with gastric cancer
    Xia, Ren-Jie
    Du, Xiao-Yu
    Shen, Li-Wen
    Ma, Jian-Guo
    Xu, Shu-Mei
    Fan, Rui-Fang
    Qin, Jian-Wei
    Yan, Long
    WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2024, 16 (09)
  • [49] Induction of tumor stem cell differentiation-novel strategy to overcome therapy resistance in gastric cancer
    Zieker, Derek
    Buehler, Sarah
    Uestuendag, Zeynep
    Koenigsrainer, Ingmar
    Manncke, Sebastian
    Bajaeifer, Khaled
    Vollmer, Joerg
    Fend, Falko
    Northoff, Hinnak
    Koenigsrainer, Alfred
    Glatzle, Joerg
    LANGENBECKS ARCHIVES OF SURGERY, 2013, 398 (04) : 603 - 608
  • [50] Failure to Tyrosine Kinase Inhibitors and Patterns of Progression in Patients with Advanced Non-Small Cell Lung Cancer
    Barron, Feliciano
    Ramirez-Tirado, Laura-Alejandra
    Caballe-Perez, Enrique
    Sanchez, Gisela
    Cardona, Andres
    Arrieta, Oscar
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (01) : S1269 - S1270