Tumor cell metaplastic programs and failure of T cell remodeling drive resistance and progression to frontline chemoimmunotherapy in advanced gastric cancer

被引:0
|
作者
Wright, Samuel J.
An, Minae
Min, Byung Hoon
Heo, You Jeong
Parikh, Milan
Bi, Lynn
Lee, Hyuk
Kim, Taejun
Lee, Song-Yi
Moon, Jeonghyeon
Park, Ryan J.
Strickland, Matthew R.
Park, Woong Yang
Kang, Won Ki
Kim, Kyoung-Mee
Kim, Seung Tae
Mehta, Arnav
Klempner, Samuel J.
Lee, Jeeyun
机构
关键词
D O I
10.1158/1538-7445.AM2024-6846
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
6846
引用
收藏
页数:2
相关论文
共 50 条
  • [31] T cell exhaustion and a failure in antigen presentation drive resistance to the graft-versus-leukemia effect
    Meng Zhou
    Faruk Sacirbegovic
    Kai Zhao
    Sarah Rosenberger
    Warren D. Shlomchik
    Nature Communications, 11
  • [32] T cell exhaustion and a failure in antigen presentation drive resistance to the graft-versus-leukemia effect
    Zhou, Meng
    Sacirbegovic, Faruk
    Zhao, Kai
    Rosenberger, Sarah
    Shlomchik, Warren D.
    NATURE COMMUNICATIONS, 2020, 11 (01)
  • [33] Overexpression of CARMA3 is associated with advanced tumor stage, cell cycle progression, and cisplatin resistance in human epithelial ovarian cancer
    Xie, Chengyao
    Han, Yong
    Fu, Lin
    Li, Qingchang
    Qiu, Xueshan
    Wang, Enhua
    TUMOR BIOLOGY, 2014, 35 (08) : 7957 - 7964
  • [34] IL-6 triggers chemoimmunotherapy resistance by creating immunosuppressive tumor microenvironment in non-small cell lung cancer
    Yang, Y.
    Liu, C.
    Yang, L.
    Yang, G.
    Hao, X.
    Zhang, S.
    ANNALS OF ONCOLOGY, 2023, 34
  • [35] Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer
    Hagel, Kimberly R.
    Arafeh, Rand
    Gang, Sydney
    Arnoff, Taylor E.
    Larson, Rebecca C.
    Doench, John G.
    Mathewson, Nathan D.
    Wucherpfennig, Kai W.
    Maus, Marcela, V
    Hahn, William C.
    CANCER RESEARCH, 2023, 83 (04) : 613 - 625
  • [36] GGT5 as a promising prognostic biomarker and its effects on tumor cell progression in gastric cancer
    Chen, Wenchao
    Yang, Fanfan
    Shen, Hao
    Xu, Jia
    Chen, Jin
    Zhang, Zhezhong
    Xu, Jian
    Xu, Bin
    TRANSLATIONAL CANCER RESEARCH, 2024, 13 (08) : 4459 - 4473
  • [37] RON is associated with tumor progression via the inhibition of apoptosis and cell cycle arrest in human gastric cancer
    Song, Young-A.
    Park, Young-Lan
    Kim, Kyu-Yeol
    Myung, Eun
    Chung, Cho-Yun
    Cho, Sung-Bum
    Lee, Wan-Sik
    Jung, Young-Do
    Kweon, Sun-Seog
    Joo, Young-Eun
    PATHOLOGY INTERNATIONAL, 2012, 62 (02) : 127 - 136
  • [38] Interleukin-32 Increases Human Gastric Cancer Cell Invasion Associated with Tumor Progression and Metastasis
    Tsai, Chung-Ying
    Wang, Chia-Siu
    Tsai, Ming-Ming
    Chi, Hsiang-Cheng
    Cheng, Wan-Li
    Tseng, Yi-Hsin
    Chen, Cheng-Yi
    Lin, Crystal D.
    Wu, Jun-I.
    Wang, Lu-Hai
    Lin, Kwang-Huei
    CLINICAL CANCER RESEARCH, 2014, 20 (09) : 2276 - 2288
  • [39] Induction of tumor stem cell differentiation—novel strategy to overcome therapy resistance in gastric cancer
    Derek Zieker
    Sarah Bühler
    Zeynep Üstündag
    Ingmar Königsrainer
    Sebastian Manncke
    Khaled Bajaeifer
    Jörg Vollmer
    Falko Fend
    Hinnak Northoff
    Alfred Königsrainer
    Jörg Glatzle
    Langenbeck's Archives of Surgery, 2013, 398 : 603 - 608
  • [40] CD155T/TIGIT Signaling Regulates CD8+ T-cell Metabolism and Promotes Tumor Progression in Human Gastric Cancer
    He, Weiling
    Zhang, Hui
    Han, Fei
    Chen, Xinlin
    Lin, Run
    Wang, Wei
    Qiu, Haibo
    Zhuang, Zhenhong
    Liao, Qi
    Zhang, Weijing
    Cai, Qinbo
    Cui, Yongmei
    Jiang, Wenting
    Wang, Han
    Ke, Zunfu
    CANCER RESEARCH, 2017, 77 (22) : 6375 - 6388