共 50 条
- [21] Discovery of MK-1084, a low dose selective clinical stage KRAS G12C inhibitorMOLECULAR CANCER THERAPEUTICS, 2023, 22 (12)Maddess, Matthew L.论文数: 0 引用数: 0 h-index: 0Sloman, David L.论文数: 0 引用数: 0 h-index: 0Ma, Xiaoshen论文数: 0 引用数: 0 h-index: 0Palani, Anandan论文数: 0 引用数: 0 h-index: 0Stoeck, Alexander论文数: 0 引用数: 0 h-index: 0Sather, Aaron C.论文数: 0 引用数: 0 h-index: 0Solban, Nicolas论文数: 0 引用数: 0 h-index: 0Duggal, Ruchia论文数: 0 引用数: 0 h-index: 0Ballard, Jeanine论文数: 0 引用数: 0 h-index: 0Munsell, Erik V.论文数: 0 引用数: 0 h-index: 0Chen, Lin-Chi论文数: 0 引用数: 0 h-index: 0Han, Yongxin论文数: 0 引用数: 0 h-index: 0Miller, Richard论文数: 0 引用数: 0 h-index: 0Gathiaka, Symon论文数: 0 引用数: 0 h-index: 0Brynczka, Christopher论文数: 0 引用数: 0 h-index: 0Li, Hongming论文数: 0 引用数: 0 h-index: 0Yang, Ruojing论文数: 0 引用数: 0 h-index: 0Brynczka, Christopher论文数: 0 引用数: 0 h-index: 0Day, Phil论文数: 0 引用数: 0 h-index: 0
- [22] A first-in-human phase 1 study of LY3537982, a highly selective and potent KRAS G12C inhibitor in patients with KRAS G12C-mutant advanced solid tumorsCANCER RESEARCH, 2023, 83 (08)Murciano-Goroff, Yonina R.论文数: 0 引用数: 0 h-index: 0Heist, Rebecca S.论文数: 0 引用数: 0 h-index: 0Kuboki, Yasutoshi论文数: 0 引用数: 0 h-index: 0Koyama, Takafumi论文数: 0 引用数: 0 h-index: 0Ammakkanavar, Natraj Reddy论文数: 0 引用数: 0 h-index: 0Hollebecque, Antoine论文数: 0 引用数: 0 h-index: 0Patnaik, Amita论文数: 0 引用数: 0 h-index: 0Shimizu, Toshio论文数: 0 引用数: 0 h-index: 0Spira, Alexander I.论文数: 0 引用数: 0 h-index: 0Nagasaka, Misako论文数: 0 引用数: 0 h-index: 0Han, Ji-Youn论文数: 0 引用数: 0 h-index: 0Iams, Wade Thomas论文数: 0 引用数: 0 h-index: 0Deming, Dustin论文数: 0 引用数: 0 h-index: 0Call, Justin论文数: 0 引用数: 0 h-index: 0Cassier, Philippe论文数: 0 引用数: 0 h-index: 0Han, Sae-Won论文数: 0 引用数: 0 h-index: 0Chu, Quincy Siu-Chung论文数: 0 引用数: 0 h-index: 0Cosman, Rasha论文数: 0 引用数: 0 h-index: 0Durm, Gregory论文数: 0 引用数: 0 h-index: 0Burns, Timothy论文数: 0 引用数: 0 h-index: 0Willard, Melinda D.论文数: 0 引用数: 0 h-index: 0Liu, Shiyao论文数: 0 引用数: 0 h-index: 0Callies, Sophie论文数: 0 引用数: 0 h-index: 0Balar, Arjun V.论文数: 0 引用数: 0 h-index: 0Sabari, Joshua K.论文数: 0 引用数: 0 h-index: 0
- [23] Discovery of potent PROTAC degraders of KRASG12C based on a reversible non-covalent KRAS binderANNALS OF ONCOLOGY, 2022, 33 : S14 - S14Zhang, Z.论文数: 0 引用数: 0 h-index: 0机构: Huadong Med, Global Drug Dev Ctr, Hangzhou, Peoples R China Huadong Med, Global Drug Dev Ctr, Hangzhou, Peoples R ChinaZhai, W.论文数: 0 引用数: 0 h-index: 0机构: Huadong Med, Global Drug Dev Ctr, Hangzhou, Peoples R China Huadong Med, Global Drug Dev Ctr, Hangzhou, Peoples R ChinaChen, H.论文数: 0 引用数: 0 h-index: 0机构: Huadong Med, Global Drug Dev Ctr, Hangzhou, Peoples R China Huadong Med, Global Drug Dev Ctr, Hangzhou, Peoples R ChinaWang, L.论文数: 0 引用数: 0 h-index: 0机构: Huadong Med, Global Drug Dev Ctr, Hangzhou, Peoples R China Huadong Med, Global Drug Dev Ctr, Hangzhou, Peoples R ChinaLiu, D.论文数: 0 引用数: 0 h-index: 0机构: Huadong Med, Global Drug Dev Ctr, Hangzhou, Peoples R China Huadong Med, Global Drug Dev Ctr, Hangzhou, Peoples R China
- [24] Discovery of Tetrahydropyridopyrimidines as Irreversible Covalent Inhibitors of KRAS-G12C with In Vivo ActivityACS MEDICINAL CHEMISTRY LETTERS, 2018, 9 (12): : 1230 - 1234Fell, Jay B.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USAFischer, John P.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USABaer, Brian R.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USABallard, Joshua论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USABlake, James F.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USABouhana, Karyn论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USABrandhuber, Barbara J.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USABriere, David M.论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut Inc, 9393 Towne Ctr Dr,Suite 200, San Diego, CA 92121 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USABurgess, Laurence E.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USABurkard, Michael R.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USAChiang, Harrah论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut Inc, 9393 Towne Ctr Dr,Suite 200, San Diego, CA 92121 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USAChicarelli, Mark J.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USADavidson, Kevin论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USAGaudino, John J.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USAHallin, Jill论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut Inc, 9393 Towne Ctr Dr,Suite 200, San Diego, CA 92121 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USAHanson, Lauren论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USAHee, Kenneth论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USAHicken, Erik J.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USAHinklin, Ronald J.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USAMarx, Matthew A.论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut Inc, 9393 Towne Ctr Dr,Suite 200, San Diego, CA 92121 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USAMejia, Macedonio J.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USAOlson, Peter论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut Inc, 9393 Towne Ctr Dr,Suite 200, San Diego, CA 92121 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USASavechenkov, Pavel论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USASudhakar, Niranjan论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut Inc, 9393 Towne Ctr Dr,Suite 200, San Diego, CA 92121 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USATang, Tony P.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USAVigers, Guy P.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USAZecca, Henry论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USAChristensen, James G.论文数: 0 引用数: 0 h-index: 0机构: Mirati Therapeut Inc, 9393 Towne Ctr Dr,Suite 200, San Diego, CA 92121 USA Array BioPharma Inc, 3200 Walnut St, Boulder, CO 80301 USA
- [25] Pan-tumor activity of olomorasib (LY3537982), a second-generation KRAS G12C inhibitor (G12Ci), in patients with KRAS G12C-mutant advanced solid tumors.JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)Heist, Rebecca Suk论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USAKoyama, Takafumi论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USAMurciano-Goroff, Yonina R.论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USAHollebecque, Antoine论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USACassier, Philippe Alexandre论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USAHan, Ji-Youn论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USATosi, Diego论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USASacher, Adrian G.论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USABurns, Timothy F.论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USASpira, Alexander I.论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USAGomez-Roca, Carlos A.论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USAShimizu, Toshio论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USAAmmakkanavar, Natraj Reddy论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USASabari, Joshua K.论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USANagasaka, Misako论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USAFink, Aaron Alan论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USAChen, Aaron论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USAWillard, Melinda D.论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USAOxnard, Geoffrey R.论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USAKuboki, Yasutoshi论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Boston, MA USA
- [26] Use of chemotype evolution to discover novel, potent, irreversible inhibitors of the oncogenic G12C mutant form of KRASABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 257Erlanson, Daniel论文数: 0 引用数: 0 h-index: 0机构: Carmot Therapeut Inc, Berkeley, CA USA Carmot Therapeut Inc, Berkeley, CA USAArvedson, Tara论文数: 0 引用数: 0 h-index: 0机构: Amgen Inc, Thousand Oaks, CA USA Carmot Therapeut Inc, Berkeley, CA USACee, Victor论文数: 0 引用数: 0 h-index: 0机构: Amgen Inc, Thousand Oaks, CA USA Carmot Therapeut Inc, Berkeley, CA USAFucini, Ray论文数: 0 引用数: 0 h-index: 0机构: Carmot Therapeut Inc, Berkeley, CA USA Carmot Therapeut Inc, Berkeley, CA USAHansen, Stig论文数: 0 引用数: 0 h-index: 0机构: Carmot Therapeut Inc, Berkeley, CA USA Carmot Therapeut Inc, Berkeley, CA USAIwig, Jeff论文数: 0 引用数: 0 h-index: 0机构: Carmot Therapeut Inc, Berkeley, CA USA Carmot Therapeut Inc, Berkeley, CA USAJeong, Joon Won论文数: 0 引用数: 0 h-index: 0机构: Carmot Therapeut Inc, Berkeley, CA USA Carmot Therapeut Inc, Berkeley, CA USAMcCarter, John论文数: 0 引用数: 0 h-index: 0机构: Amgen Inc, Thousand Oaks, CA USA Carmot Therapeut Inc, Berkeley, CA USASabet, Sudi论文数: 0 引用数: 0 h-index: 0机构: Carmot Therapeut Inc, Berkeley, CA USA Carmot Therapeut Inc, Berkeley, CA USASawayama, Andrew论文数: 0 引用数: 0 h-index: 0机构: Carmot Therapeut Inc, Berkeley, CA USA Carmot Therapeut Inc, Berkeley, CA USASethofer, Steven论文数: 0 引用数: 0 h-index: 0机构: Carmot Therapeut Inc, Berkeley, CA USA Carmot Therapeut Inc, Berkeley, CA USA
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