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- [4] Discovery of Quinazoline Derivatives as Potent KRASG12C InhibitorsCHEMISTRYSELECT, 2024, 9 (39):Liu, NianLi, ZhilongLiu, RuiZhang, ChaoxinSun, YixiangMa, XingQin, QiaohuaWu, TianxiaoSun, YinYin, WenboZhang, HaoyuGao, ZixuanXia, GuangxinZhao, DongmeiCheng, Maosheng
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- [6] Optimization of quinazolinone-based covalent inhibitors of KRASG12C in the discovery of AMG 510ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 258Lopez, PatriciaAllen, JenniferAllen, JohnAmegadzie, AlbertAshton, KateBooker, ShonChen, JianChen, NingFrohn, MichaelGoodman, GuyKopecky, DavidLiu, LongbinLow, JonathanMa, VuNguyen, ThomasNishimura, NobukoPickrell, AlexanderReed, AnthonyShin, YoungsookSiegmund, AaronTamayo, NuriaTegley, ChristopherWalton, MaryWang, Hui-LingWurz, RyanXue, MayYang, KevinAchanta, PragathiBartberger, MichaelCanon, JudeMcCarter, JohnMohr, ChristopherRex, KarenSaiki, AnneSan Miguel, TishaVolak, LaurieWang, KevinWhittington, DouglasLipford, J. RussellCee, VictorLanman, Brian
- [7] A Potent SOS1 PROTAC Degrader with Synergistic Efficacy in Combination with KRASG12C InhibitorJOURNAL OF MEDICINAL CHEMISTRY, 2024, 67 (04) : 2487 - 2511Lv, YanYang, ZixuanChen, YimingMa, XuepeiGuo, MengqiZhang, ChengweiJiang, XiaolinWang, ChengliLi, ZhuoyueTai, ZhengfuWang, XiaoZhang, SiqiMa, ShuminQin, Chong
- [8] Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C InhibitorJOURNAL OF MEDICINAL CHEMISTRY, 2022, 65 (21) : 14614 - 14629Broeker, JoachimWaterson, Alex G.Smethurst, ChrisKessler, DirkBoettcher, JarkMayer, MorizGmaschitz, GerhardPhan, JasonLittle, AndrewAbbott, Jason R.Sun, QiGmachl, MichaelRudolph, DorotheaArnhof, HeribertRumpel, KlausSavarese, FabioGerstberger, ThomasMischerikow, NikolaiTreu, MatthiasHerdeis, LorenzWunberg, TobiasGollner, AndreasWeinstabl, HaraldMantoulidis, AndreasKraemer, OliverMcConnell, Darryl B.Fesik, Stephen W.
- [9] Discovery of AZD4625, a Covalent Allosteric Inhibitor of the MutantGTPase KRASG12CJOURNAL OF MEDICINAL CHEMISTRY, 2022, 65 (09) : 6940 - 6952Kettle, Jason G.Bagal, Sharan K.Bickerton, SueBodnarchuk, Michael S.Boyd, ScottBreed, JasonCarbajo, Rodrigo J.Cassar, Doyle J.Chakraborty, AtanuCosulich, SabinaCumming, IainDavies, MichaelDavies, Nichola L.Eatherton, AndrewEvans, LauraFeron, LymanFillery, ShaunGleave, Emma S.Goldberg, Frederick W.Hanson, LyndseyHarlfinger, StephanieHoward, MartinHowells, RachelJackson, AnneKemmitt, PaulLamont, GillianLamont, ScottLewis, Hilary J.Liu, LibinNiedbala, Michael J.Phillips, ChristopherPolanski, RadekRaubo, PiotrRobb, GraemeRobinson, David M.Ross, SarahSanders, Matthew G.Tonge, MichaelWhiteley, RebeccaWilkinson, StephenYang, JunshengZhang, Wenman
- [10] Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid TumorsJOURNAL OF MEDICINAL CHEMISTRY, 2020, 63 (01) : 52 - 65Lanman, Brian A.Allen, Jennifer R.Allen, John G.Amegadzie, Albert K.Ashton, Kate S.Booker, Shon K.Chen, Jian JeffreyChen, NingFrohn, Michael J.Goodman, GuyKopecky, David J.Liu, LongbinLopez, PatriciaLow, Jonathan D.Ma, VuMinatti, Ana E.Nguyen, Thomas T.Nishimura, NobukoPickrell, Alexander J.Reed, Anthony B.Shin, YoungsookSiegmund, Aaron C.Tamayo, Nuria A.Tegley, Christopher M.Walton, Mary C.Wang, Hui-LingWurz, Ryan P.Xue, MayYang, Kevin C.Achanta, PragathiBartberger, Michael D.Canon, JudeHollis, L. StevenMcCarter, John D.Mohr, ChristopherRex, KarenSaiki, Anne Y.San Miguel, TishaVolak, Laurie P.Wang, Kevin H.Whittington, Douglas A.Zech, Stephan G.Lipford, J. RussellCee, Victor J.