Reduced 123I Ioflupane Binding in Bilateral Diabetic Chorea: Findings With 18F FDG PET, 99mTc ECD SPECT, and 123I MIBG Scintigraphy

被引：8

作者：

Sato, Kenichiro ^{[1
]}

Hida, Ayumi ^{[1
]}

Kameyama, Masashi ^{[2
]}

Morooka, Miyako ^{[2
]}

Takeuchi, Sousuke ^{[1
]}

机构：

[1] Natl Ctr Global Hlth & Med, Dept Neurol, Shinjuku Ku, Tokyo, Japan

[2] Natl Ctr Global Hlth & Med, Dept Radiol, Div Nucl Med, Shinjuku Ku, Tokyo, Japan

来源：

CLINICAL NUCLEAR MEDICINE | 2016年 / 41卷 / 06期

关键词：

diabetic chorea; I-123; ioflupane; dopamine transporter SPECT; F-18 FDG PET; I-123 MIBG scintigraphy; HYPERGLYCEMIA; HEMICHOREA;

D O I：

10.1097/RLU.0000000000001202

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

We report a 64-year-old man with diabetic chorea whom we investigated with dopamine transporter SPECT, F-18 FDG PET, Tc-99m ethylcysteinate dimer (ECD) SPECT, and I-123 metaiodobenzylguanidine (MIBG) scintigraphy. Dopamine transporter SPECT revealed reduced I-123 ioflupane binding in the bilateral striatum. F-18 FDG PET showed metabolic dysfunction in the bilateral striatum, as shown in earlier studies. Tc-99m ECD SPECT revealed reduced brain perfusion in the bilateral caudate nucleus and putamen. I-123 MIBG scintigraphy revealed no cardiac sympathetic nerve dysfunction. Our case suggests a possible nigrostriatal presynaptic dopaminergic involvement in diabetic chorea.

引用

页码：481 / 482

页数：2

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