Reduced 123I Ioflupane Binding in Bilateral Diabetic Chorea: Findings With 18F FDG PET, 99mTc ECD SPECT, and 123I MIBG Scintigraphy

被引：8
|
作者：
Sato, Kenichiro [1 ]
Hida, Ayumi [1 ]
Kameyama, Masashi [2 ]
Morooka, Miyako [2 ]
Takeuchi, Sousuke [1 ]
机构：
[1] Natl Ctr Global Hlth & Med, Dept Neurol, Shinjuku Ku, Tokyo, Japan
[2] Natl Ctr Global Hlth & Med, Dept Radiol, Div Nucl Med, Shinjuku Ku, Tokyo, Japan
来源：
CLINICAL NUCLEAR MEDICINE | 2016年 / 41卷 / 06期
关键词：
diabetic chorea; I-123; ioflupane; dopamine transporter SPECT; F-18 FDG PET; I-123 MIBG scintigraphy; HYPERGLYCEMIA; HEMICHOREA;
D O I：
10.1097/RLU.0000000000001202
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
We report a 64-year-old man with diabetic chorea whom we investigated with dopamine transporter SPECT, F-18 FDG PET, Tc-99m ethylcysteinate dimer (ECD) SPECT, and I-123 metaiodobenzylguanidine (MIBG) scintigraphy. Dopamine transporter SPECT revealed reduced I-123 ioflupane binding in the bilateral striatum. F-18 FDG PET showed metabolic dysfunction in the bilateral striatum, as shown in earlier studies. Tc-99m ECD SPECT revealed reduced brain perfusion in the bilateral caudate nucleus and putamen. I-123 MIBG scintigraphy revealed no cardiac sympathetic nerve dysfunction. Our case suggests a possible nigrostriatal presynaptic dopaminergic involvement in diabetic chorea.
引用
收藏
页码：481 / 482
页数：2
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