Influences of bacterial extracellular vesicles on macrophage immune functions

被引:0
|
作者
Jiang, Bowei [1 ]
Huang, Junyun [2 ]
机构
[1] Gannan Med Univ, Sch Clin Med 1, Ganzhou, Peoples R China
[2] Gannan Med Univ, Affiliated Hosp 1, Dept Lab Med, Ganzhou, Peoples R China
关键词
extracellular vesicles; bacterial; macrophage; immune; influences; OUTER-MEMBRANE VESICLES; CELL; ACTIVATION; HOST; BIOGENESIS; MECHANISMS;
D O I
10.3389/fcimb.2024.1411196
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Bacterial extracellular vesicles (EVs) are crucial mediators of information transfer between bacteria and host cells. Macrophages, as key effector cells in the innate immune system, have garnered widespread attention for their interactions with bacterial EVs. Increasing evidence indicates that bacterial EVs can be internalized by macrophages through multiple pathways, thereby influencing their immune functions. These functions include inflammatory responses, antimicrobial activity, antigen presentation, and programmed cell death. Therefore, this review summarizes current research on the interactions between bacterial EVs and macrophages. This will aid in the deeper understanding of immune modulation mediated by pathogenic microorganisms and provide a basis for developing novel antibacterial therapeutic strategies.
引用
收藏
页数:7
相关论文
共 50 条
  • [31] Extracellular vesicles and microvilli in the immune synapse
    Ruiz-Navarro, Javier
    Calvo, Victor
    Izquierdo, Manuel
    FRONTIERS IN IMMUNOLOGY, 2024, 14
  • [32] Functions of Extracellular Vesicles in Immunity and Virulence
    Rybak, Katarzyna
    Robatzek, Silke
    PLANT PHYSIOLOGY, 2019, 179 (04) : 1236 - 1247
  • [33] Extracellular Vesicles in Fungi: Composition and Functions
    Martins, Sharon de Toledo
    Szwarc, Paulo
    Goldenberg, Samuel
    Alves, Lysangela Ronalte
    FUNGAL PHYSIOLOGY AND IMMUNOPATHOGENESIS, 2019, 422 : 44 - +
  • [34] Functions of extracellular vesicles and their application as biomarkers
    Reiners, Katrin S.
    Dassler-Plenker, Juliane
    Coch, Christoph
    Hartmann, Gunther
    LABORATORIUMSMEDIZIN-JOURNAL OF LABORATORY MEDICINE, 2017, 41 (06): : 299 - 308
  • [35] Functions and importance of mycobacterial extracellular vesicles
    Rodriguez, G. Marcela
    Prados-Rosales, Rafael
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2016, 100 (09) : 3887 - 3892
  • [36] Extracellular vesicles and their immunomodulatory functions in pregnancy
    Nair, Soumyalekshmi
    Salomon, Carlos
    SEMINARS IN IMMUNOPATHOLOGY, 2018, 40 (05) : 425 - 437
  • [37] Extracellular vesicles and their immunomodulatory functions in pregnancy
    Soumyalekshmi Nair
    Carlos Salomon
    Seminars in Immunopathology, 2018, 40 : 425 - 437
  • [38] Extracellular Vesicles and Immune System in Ageing and Immune Diseases
    Cheon, So Yeong
    Lee, Jong Eun
    EXPERIMENTAL NEUROBIOLOGY, 2021, 30 (01) : 32 - 47
  • [39] IMMUNE FUNCTIONS OF ALVEOLAR MACROPHAGE
    DANIELE, RP
    DAUBER, JH
    GORENBERG, DJ
    CLINICAL RESEARCH, 1978, 26 (03): : A557 - A557
  • [40] Priming of macrophage by glycosphingolipids from extracellular vesicles facilitates immune tolerance for embryo-maternal crosstalk
    Lo, Tzu-Chi
    Cheng, Jing-Yan
    Lee, Chien-Wei
    Hung, Jung-Tung
    Lin, Chun-Cheng
    Yeh, Hsiao-Fong
    Yang, Bei -Chia
    Huang, Yenlin
    Wu, Hsien-Ming
    Yu, Alice L.
    Yu, John
    DEVELOPMENTAL CELL, 2023, 58 (22) : 2447 - +