Electrochemical Benzylic C-H Amination via N-Aminopyridinium

被引：1

作者：

Liu, Jingwei ^{[1
]}

Du, Jinyao ^{[1
]}

Zhang, Lin-Bao ^{[1
]}

Li, Ming ^{[1
]}

Guo, Weisi ^{[1
]}

机构：

[1] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 89卷 / 09期

关键词：

C(SP(3))-H BONDS; SALTS;

D O I：

10.1021/acs.joc.4c00502

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An electrochemical protocol for benzylic C(sp(3))-H aminopyridylation via direct C-H/N-H cross-coupling of alkylarenes with N-aminopyridinium triflate has been developed. This method features excellent site-selectivity, broad substrate scope, redox reagent-free and facile scalability. The generated benzylaminopyridiniums can be readily converted to benzylamines via electroreductive N-N bond cleavage.

引用

页码：6465 / 6473

页数：9

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