HLA-Haploidentical Peripheral Blood Stem Cell Transplantation with Post-Transplantation Cyclophosphamide versus HLA-Matched Unrelated Donor Transplantation for Myelodysplastic Syndrome

被引：0

作者：

Nakaya, Yosuke ^{[1
]}

Koh, Hideo ^{[2
]}

Konuma, Takaaki ^{[3
]}

Shimomura, Yoshimitsu ^{[4
,5
]}

Ishiyama, Ken ^{[6
]}

Itonaga, Hidehiro ^{[7
]}

Hino, Masayuki ^{[1
]}

Doki, Noriko ^{[8
]}

Nishida, Tetsuya ^{[9
]}

Ohigashi, Hiroyuki ^{[10
]}

Matsuoka, Ken-ichi ^{[11
]}

Kanda, Yoshinobu ^{[12
]}

Maruyama, Yumiko ^{[13
]}

Sawa, Masashi ^{[14
]}

Eto, Tetsuya ^{[15
]}

Hiramoto, Nobuhiro ^{[4
]}

Fukuda, Takahiro ^{[16
]}

Atsuta, Yoshiko ^{[17
,18
]}

Nakamae, Hirohisa ^{[1
]}

机构：

[1] Osaka Metropolitan Univ, Grad Sch Med, Dept Hematol, Osaka, Japan

[2] Osaka Metropolitan Univ, Grad Sch Med, Dept Prevent Med & Environm Hlth, Osaka, Japan

[3] Univ Tokyo, Inst Med Sci, Dept Hematol Oncol, Tokyo, Japan

[4] Kobe City Med Ctr Gen Hosp, Dept Hematol, Kobe, Japan

[5] Osaka Univ, Grad Sch Med, Dept Environm Med & Populat Sci, Suita, Japan

[6] Natl Ctr Global Hlth & Med, Dept Hematol, Tokyo, Japan

[7] Nagasaki Univ Hosp, Transfus & Cell Therapy Unit, Nagasaki, Japan

[8] Komagome Hosp, Tokyo Metropolitan Canc & Infect Dis Ctr, Hematol Div, Tokyo, Japan

[9] Nagoya Daiichi Hosp, Japanese Red Cross Aichi Med Ctr, Dept Hematol, Nagoya, Japan

[10] Hokkaido Univ Hosp, Dept Hematol, Sapporo, Japan

[11] Okayama Univ Hosp, Dept Hematol & Oncol, Okayama, Japan

[12] Jichi Med Univ, Saitama Med Ctr, Div Hematol, Saitama, Japan

[13] Univ Tsukuba Hosp, Dept Hematol, Tsukuba, Japan

[14] Anjo Kosei Hosp, Dept Hematol & Oncol, Anjo, Japan

[15] Hamanomachi Hosp, Dept Hematol, Fukuoka, Japan

[16] Natl Canc Ctr, Dept Hematopoiet Stem Cell Transplantat, Tokyo, Japan

[17] Japanese Data Ctr Hematopoiet Cell Transplantat, Nagoya, Japan

[18] Aichi Med Univ, Sch Med, Dept Registry Sci Transplant & Cellular Therapy, Nagakute, Japan

来源：

TRANSPLANTATION AND CELLULAR THERAPY | 2024年 / 30卷 / 03期

关键词：

Myelodysplastic; syndrome; Peripheral blood stem; cell transplantation; Haploidentical donor; Matched unrelated donor; Post-transplantation; cyclophosphamide; BONE-MARROW-TRANSPLANTATION; WORLD-HEALTH-ORGANIZATION; MYELOID NEOPLASMS; ACUTE-LEUKEMIA; TRUMP DATA; IMPACT; CLASSIFICATION; DISPARITY; SURVIVAL; REVISION;

D O I：

10.1016/j.jtct.2023.10.021

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Allogeneic hematopoietic cell transplantation (allo-HCT) is the sole curative therapy for myelodysplastic syndrome (MDS). In the absence of an HLA-matched sibling donor, an HLA-matched unrelated donor (MUD) is considered the leading candidate. However, in recent decades, the alternative donor pool has been extended to HLA-haploidentical donors, especially with the development of graft -versus -host disease (GVHD) prophylaxis using post -transplantation cyclophosphamide (PTCy). Comparative data for haploidentical

引用

页数：12

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